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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF19 All Species: 20.91
Human Site: S556 Identified Species: 38.33
UniProt: Q2TAC6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TAC6 NP_694941.2 998 111332 S556 T L P R R I G S E E Q R E V L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088370 998 111181 S556 T L P R R I G S E E Q R E V L
Dog Lupus familis XP_540404 1004 111873 S556 T L P R R I G S E E Q R Q V L
Cat Felis silvestris
Mouse Mus musculus Q99PT9 997 111540 S555 T L P R R I G S E E Q R E V L
Rat Rattus norvegicus Q4KLL9 826 91176 L409 R S P Q P P K L S I P Q N L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513554 1018 116998 N551 L L P K H I I N E D Q R E V L
Chicken Gallus gallus Q5ZLK6 797 86563 E380 I C E Q L K T E V A D L Q A K
Frog Xenopus laevis Q7ZXX2 997 114958 S553 A L P K R I S S D D Q R E I L
Zebra Danio Brachydanio rerio Q58G59 1363 154819 A803 E C R R K I A A A Q S K V Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 A924 D A K P K Y R A L N E K D D V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46873 699 78760 S282 K H I P Y R D S K L T R L L Q
Sea Urchin Strong. purpuratus P46872 699 78679 S282 S T L G N V I S S L V D G K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 S493 N E R L I S E S N E F K M Q L
Conservation
Percent
Protein Identity: 100 N.A. 94.8 88.9 N.A. 89.6 29.8 N.A. 45.4 31 64.2 25 N.A. 23.1 N.A. 26 26.1
Protein Similarity: 100 N.A. 96.4 92 N.A. 93.3 47.4 N.A. 61.9 46.4 76.6 40.2 N.A. 36.1 N.A. 41.7 42.2
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 6.6 N.A. 60 0 60 13.3 N.A. 0 N.A. 13.3 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 26.6 N.A. 80 13.3 86.6 46.6 N.A. 40 N.A. 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 22.9
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 43.6
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 8 16 8 8 0 0 0 8 0 % A
% Cys: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 8 0 8 16 8 8 8 8 0 % D
% Glu: 8 8 8 0 0 0 8 8 39 39 8 0 39 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 31 0 0 0 0 0 8 0 0 % G
% His: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 8 0 8 54 16 0 0 8 0 0 0 8 0 % I
% Lys: 8 0 8 16 16 8 8 0 8 0 0 24 0 8 8 % K
% Leu: 8 47 8 8 8 0 0 8 8 16 0 8 8 16 54 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 0 0 0 8 0 0 8 8 8 0 0 8 0 0 % N
% Pro: 0 0 54 16 8 8 0 0 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 16 0 0 0 0 0 8 47 8 16 16 8 % Q
% Arg: 8 0 16 39 39 8 8 0 0 0 0 54 0 0 0 % R
% Ser: 8 8 0 0 0 8 8 62 16 0 8 0 0 0 16 % S
% Thr: 31 8 0 0 0 0 8 0 0 0 8 0 0 0 0 % T
% Val: 0 0 0 0 0 8 0 0 8 0 8 0 8 39 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _