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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF19
All Species:
10
Human Site:
S754
Identified Species:
18.33
UniProt:
Q2TAC6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TAC6
NP_694941.2
998
111332
S754
L
G
S
W
I
N
S
S
P
D
S
S
E
N
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088370
998
111181
S754
L
G
S
W
I
S
S
S
P
D
S
S
E
I
L
Dog
Lupus familis
XP_540404
1004
111873
P762
S
S
Q
I
T
S
S
P
D
S
S
E
N
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99PT9
997
111540
S753
L
G
S
Q
I
N
S
S
P
E
S
S
E
N
L
Rat
Rattus norvegicus
Q4KLL9
826
91176
L597
M
A
K
Q
L
S
G
L
T
H
T
L
G
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513554
1018
116998
I618
A
L
I
K
E
H
C
I
S
V
P
E
L
L
E
Chicken
Gallus gallus
Q5ZLK6
797
86563
A568
P
S
V
P
T
T
R
A
A
L
R
R
L
Q
Q
Frog
Xenopus laevis
Q7ZXX2
997
114958
N751
Y
L
P
R
N
Q
I
N
Y
F
P
D
S
T
D
Zebra Danio
Brachydanio rerio
Q58G59
1363
154819
G1006
R
N
G
L
L
R
S
G
S
A
Q
D
S
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZAJ2
1670
189326
Y1253
I
Y
I
T
L
S
A
Y
L
E
L
E
N
C
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46873
699
78760
K470
E
A
E
T
K
T
Q
K
L
A
A
A
L
N
V
Sea Urchin
Strong. purpuratus
P46872
699
78679
L470
Q
K
I
L
N
E
K
L
N
A
I
Q
K
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
K681
L
A
K
S
L
S
D
K
S
A
V
Q
V
E
L
Conservation
Percent
Protein Identity:
100
N.A.
94.8
88.9
N.A.
89.6
29.8
N.A.
45.4
31
64.2
25
N.A.
23.1
N.A.
26
26.1
Protein Similarity:
100
N.A.
96.4
92
N.A.
93.3
47.4
N.A.
61.9
46.4
76.6
40.2
N.A.
36.1
N.A.
41.7
42.2
P-Site Identity:
100
N.A.
86.6
13.3
N.A.
86.6
0
N.A.
0
0
0
6.6
N.A.
0
N.A.
6.6
6.6
P-Site Similarity:
100
N.A.
93.3
20
N.A.
93.3
26.6
N.A.
6.6
6.6
6.6
13.3
N.A.
33.3
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
0
0
0
0
8
8
8
31
8
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
8
0
8
16
0
16
0
0
8
% D
% Glu:
8
0
8
0
8
8
0
0
0
16
0
24
24
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
24
8
0
0
0
8
8
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
24
8
24
0
8
8
0
0
8
0
0
16
0
% I
% Lys:
0
8
16
8
8
0
8
16
0
0
0
0
8
8
0
% K
% Leu:
31
16
0
16
31
0
0
16
16
8
8
8
24
16
39
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
16
16
0
8
8
0
0
0
16
24
0
% N
% Pro:
8
0
8
8
0
0
0
8
24
0
16
0
0
0
8
% P
% Gln:
8
0
8
16
0
8
8
0
0
0
8
16
0
16
16
% Q
% Arg:
8
0
0
8
0
8
8
0
0
0
8
8
0
0
0
% R
% Ser:
8
16
24
8
0
39
39
24
24
8
31
24
16
0
8
% S
% Thr:
0
0
0
16
16
16
0
0
8
0
8
0
0
8
0
% T
% Val:
0
0
8
0
0
0
0
0
0
8
8
0
8
0
8
% V
% Trp:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _