KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF19
All Species:
13.64
Human Site:
T776
Identified Species:
25
UniProt:
Q2TAC6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TAC6
NP_694941.2
998
111332
T776
K
E
R
K
E
I
L
T
G
T
K
C
I
W
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088370
998
111181
T776
K
E
R
K
E
I
M
T
G
T
K
C
I
S
V
Dog
Lupus familis
XP_540404
1004
111873
G784
E
R
K
E
I
L
T
G
T
K
C
I
S
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99PT9
997
111540
T775
K
E
R
K
E
I
L
T
R
T
K
C
I
S
V
Rat
Rattus norvegicus
Q4KLL9
826
91176
T619
D
K
T
S
Q
K
P
T
K
E
K
K
R
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513554
1018
116998
L640
R
E
L
E
E
G
T
L
N
R
L
L
L
Q
H
Chicken
Gallus gallus
Q5ZLK6
797
86563
R590
K
L
V
A
K
K
R
R
R
S
E
M
S
N
T
Frog
Xenopus laevis
Q7ZXX2
997
114958
T773
R
E
K
K
E
I
T
T
S
I
Q
S
I
A
V
Zebra Danio
Brachydanio rerio
Q58G59
1363
154819
L1028
L
R
Q
E
K
E
L
L
L
K
Q
R
V
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZAJ2
1670
189326
G1275
D
L
S
M
V
I
Y
G
R
D
A
R
T
G
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46873
699
78760
E492
Q
V
Y
S
T
T
Q
E
K
L
D
A
V
T
S
Sea Urchin
Strong. purpuratus
P46872
699
78679
E492
L
A
K
S
E
E
Q
E
Q
L
L
E
Q
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
T703
I
A
L
K
N
S
E
T
E
H
L
K
A
L
V
Conservation
Percent
Protein Identity:
100
N.A.
94.8
88.9
N.A.
89.6
29.8
N.A.
45.4
31
64.2
25
N.A.
23.1
N.A.
26
26.1
Protein Similarity:
100
N.A.
96.4
92
N.A.
93.3
47.4
N.A.
61.9
46.4
76.6
40.2
N.A.
36.1
N.A.
41.7
42.2
P-Site Identity:
100
N.A.
86.6
0
N.A.
86.6
13.3
N.A.
13.3
6.6
46.6
6.6
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
N.A.
93.3
26.6
N.A.
86.6
33.3
N.A.
33.3
26.6
66.6
46.6
N.A.
6.6
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
8
0
0
0
0
0
0
8
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
24
0
0
0
% C
% Asp:
16
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% D
% Glu:
8
39
0
24
47
16
8
16
8
8
8
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
16
16
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% H
% Ile:
8
0
0
0
8
39
0
0
0
8
0
8
31
0
0
% I
% Lys:
31
8
24
39
16
16
0
0
16
16
31
16
0
8
8
% K
% Leu:
16
16
16
0
0
8
24
16
8
16
24
8
8
8
16
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
8
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% P
% Gln:
8
0
8
0
8
0
16
0
8
0
16
0
8
8
0
% Q
% Arg:
16
16
24
0
0
0
8
8
24
8
0
16
8
0
0
% R
% Ser:
0
0
8
24
0
8
0
0
8
8
0
8
16
24
8
% S
% Thr:
0
0
8
0
8
8
24
47
8
24
0
0
8
8
8
% T
% Val:
0
8
8
0
8
0
0
0
0
0
0
0
16
8
39
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _