KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMTNL2
All Species:
12.12
Human Site:
S232
Identified Species:
33.33
UniProt:
Q2TAL5
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TAL5
NP_001108446.1
461
50196
S232
G
G
L
N
P
S
P
S
E
V
I
T
P
W
T
Chimpanzee
Pan troglodytes
XP_508434
474
50826
D236
P
S
E
E
Q
E
Q
D
V
E
K
E
P
E
G
Rhesus Macaque
Macaca mulatta
XP_001094503
461
49839
S232
G
G
L
N
P
S
P
S
E
A
T
T
P
W
T
Dog
Lupus familis
XP_848449
709
75820
G481
P
T
S
A
A
V
L
G
A
L
S
L
S
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI12
456
49505
S228
G
G
F
T
P
S
P
S
E
A
I
S
P
W
T
Rat
Rattus norvegicus
XP_001053796
456
49561
S228
G
G
F
T
P
S
P
S
E
A
I
S
P
W
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511797
507
55877
G275
G
S
P
S
K
I
P
G
E
V
A
T
R
T
S
Chicken
Gallus gallus
XP_415932
468
51770
N234
L
G
Q
N
Q
S
K
N
E
M
T
L
K
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997970
493
53308
S264
D
N
Q
P
Q
L
E
S
P
V
H
A
V
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.3
94.7
51.7
N.A.
83.9
83.9
N.A.
45.5
53.8
N.A.
46
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
41.3
96.5
56.4
N.A.
91.3
90.4
N.A.
53.4
70.5
N.A.
59.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
86.6
0
N.A.
73.3
73.3
N.A.
33.3
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
86.6
13.3
N.A.
80
80
N.A.
46.6
46.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
12
0
0
0
12
34
12
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
0
0
12
12
0
12
12
0
67
12
0
12
0
12
0
% E
% Phe:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
56
56
0
0
0
0
0
23
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
0
0
12
0
0
0
0
34
0
0
0
0
% I
% Lys:
0
0
0
0
12
0
12
0
0
0
12
0
12
0
0
% K
% Leu:
12
0
23
0
0
12
12
0
0
12
0
23
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
12
0
34
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
23
0
12
12
45
0
56
0
12
0
0
0
56
12
0
% P
% Gln:
0
0
23
0
34
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% R
% Ser:
0
23
12
12
0
56
0
56
0
0
12
23
12
12
45
% S
% Thr:
0
12
0
23
0
0
0
0
0
0
23
34
0
23
45
% T
% Val:
0
0
0
0
0
12
0
0
12
34
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
45
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _