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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUSC1 All Species: 11.82
Human Site: T138 Identified Species: 28.89
UniProt: Q2TAM9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TAM9 NP_001004125.1 212 23390 T138 R V P E E A S T N R R A R D S
Chimpanzee Pan troglodytes XP_001153427 212 23584 T138 R V P E E A S T N R R A R D S
Rhesus Macaque Macaca mulatta XP_001106111 211 23249 T137 R V P E E A S T N R R A T D S
Dog Lupus familis XP_533988 370 43364 Q211 E K E L L E L Q N Q Q A C A H
Cat Felis silvestris
Mouse Mus musculus Q673H1 205 22694 T131 L A P D E P A T N R K A R G H
Rat Rattus norvegicus B2RZ86 370 43435 E206 Q A R A R E E E L L A L Q N Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509898 202 22689 Q125 A A P G G G E Q K R P P L G G
Chicken Gallus gallus XP_424937 234 25814 A137 G S D G E A E A L R A Q L D R
Frog Xenopus laevis Q7ZW57 334 39474 H201 K V S E E T R H E A Q E K L A
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781766 342 40404 Q214 Q M K E V L A Q L K Q E R D S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.2 91.5 25.6 N.A. 73.1 22.9 N.A. 56.5 41.8 23.6 N.A. N.A. N.A. N.A. N.A. 20.1
Protein Similarity: 100 96.6 92.9 34.8 N.A. 79.7 33.2 N.A. 61.3 50.4 36.5 N.A. N.A. N.A. N.A. N.A. 35.9
P-Site Identity: 100 100 93.3 13.3 N.A. 46.6 0 N.A. 13.3 26.6 20 N.A. N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 93.3 26.6 N.A. 66.6 20 N.A. 13.3 26.6 46.6 N.A. N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 30 0 10 0 40 20 10 0 10 20 50 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 10 10 0 0 0 0 0 0 0 0 0 50 0 % D
% Glu: 10 0 10 50 60 20 30 10 10 0 0 20 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 20 10 10 0 0 0 0 0 0 0 20 10 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 20 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 10 10 0 0 0 0 0 10 10 10 0 10 0 0 % K
% Leu: 10 0 0 10 10 10 10 0 30 10 0 10 20 10 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 50 0 0 0 0 10 0 % N
% Pro: 0 0 50 0 0 10 0 0 0 0 10 10 0 0 0 % P
% Gln: 20 0 0 0 0 0 0 30 0 10 30 10 10 0 10 % Q
% Arg: 30 0 10 0 10 0 10 0 0 60 30 0 40 0 10 % R
% Ser: 0 10 10 0 0 0 30 0 0 0 0 0 0 0 40 % S
% Thr: 0 0 0 0 0 10 0 40 0 0 0 0 10 0 0 % T
% Val: 0 40 0 0 10 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _