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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATG2A All Species: 19.09
Human Site: S181 Identified Species: 38.18
UniProt: Q2TAZ0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TAZ0 NP_055919 1938 212919 S181 T V V R V E H S P G D G E R G
Chimpanzee Pan troglodytes XP_508535 1868 205411 V184 S G Y M E L M V K L K Q N E A
Rhesus Macaque Macaca mulatta XP_001114733 1938 213060 S181 T V V R V E H S P G D G E R G
Dog Lupus familis XP_540877 1960 215268 S213 T V V R V E H S S G D G E H G
Cat Felis silvestris
Mouse Mus musculus Q6P4T0 1914 210921 S181 T V V R V E H S L G D E D R S
Rat Rattus norvegicus NP_001103015 1916 211346 S181 T V V R V E H S L G D E E R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512043 2088 234252 V189 T V L R I E H V P E N S K T G
Chicken Gallus gallus XP_421350 2043 229447 S206 D E T A D E C S G I N V H Q P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002664934 1738 194462 S133 Y S A S L G E S P S G N V A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647748 1906 214898 I181 T T L N I E Y I L P R S D R K
Honey Bee Apis mellifera XP_001122229 1976 220972 V181 T V I R L E H V P L D S S T G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792926 2119 235171 S230 S P S S S P S S A D L V E D G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.9 97.6 89.5 N.A. 84.7 85.1 N.A. 41.3 42 N.A. 36.5 N.A. 28.5 31.1 N.A. 30.9
Protein Similarity: 100 91.4 98.2 92.5 N.A. 90.4 90.4 N.A. 57.3 59.3 N.A. 51.9 N.A. 47 48.7 N.A. 48.8
P-Site Identity: 100 0 100 86.6 N.A. 73.3 80 N.A. 46.6 13.3 N.A. 13.3 N.A. 20 53.3 N.A. 20
P-Site Similarity: 100 6.6 100 86.6 N.A. 80 80 N.A. 73.3 26.6 N.A. 20 N.A. 46.6 66.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 0 0 0 0 9 0 0 0 0 9 9 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 9 0 0 0 0 9 50 0 17 9 0 % D
% Glu: 0 9 0 0 9 75 9 0 0 9 0 17 42 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 9 0 0 9 42 9 25 0 0 50 % G
% His: 0 0 0 0 0 0 59 0 0 0 0 0 9 9 0 % H
% Ile: 0 0 9 0 17 0 0 9 0 9 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 9 0 9 0 9 0 9 % K
% Leu: 0 0 17 0 17 9 0 0 25 17 9 0 0 0 0 % L
% Met: 0 0 0 9 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 17 9 9 0 0 % N
% Pro: 0 9 0 0 0 9 0 0 42 9 0 0 0 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % Q
% Arg: 0 0 0 59 0 0 0 0 0 0 9 0 0 42 0 % R
% Ser: 17 9 9 17 9 0 9 67 9 9 0 25 9 0 17 % S
% Thr: 67 9 9 0 0 0 0 0 0 0 0 0 0 17 9 % T
% Val: 0 59 42 0 42 0 0 25 0 0 0 17 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _