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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASTE1 All Species: 7.58
Human Site: S248 Identified Species: 20.83
UniProt: Q2TB18 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TB18 NP_054784.2 679 77093 S248 L P L G A T S S K G R R H H R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001113246 520 58840 H104 R E R I Q M A H S L S V G G S
Dog Lupus familis XP_853344 461 52096 L45 R L C F N S N L E L R Y G G D
Cat Felis silvestris
Mouse Mus musculus Q8BIR2 672 76352 S246 K V R L P L S S K G R R Y H R
Rat Rattus norvegicus NP_001035246 672 76539 S246 K V R L P F S S K G R R Y H R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514361 662 75505 S245 V D L H A G T S R F K G K R H
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LYL8 692 79210 N242 R H W E R Y S N P G S E N P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VPW1 854 98358 L323 L A K V L S R L K K N Q R D S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792821 720 80781 G249 N G K C G G S G S R R Q M E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 72.4 60.9 N.A. 78.1 79.2 N.A. 64.8 N.A. N.A. 35.9 N.A. 23 N.A. N.A. 30.2
Protein Similarity: 100 N.A. 75.1 64.5 N.A. 86.7 87 N.A. 77.6 N.A. N.A. 52.4 N.A. 37.7 N.A. N.A. 47.7
P-Site Identity: 100 N.A. 0 6.6 N.A. 53.3 53.3 N.A. 20 N.A. N.A. 13.3 N.A. 13.3 N.A. N.A. 13.3
P-Site Similarity: 100 N.A. 6.6 26.6 N.A. 60 60 N.A. 46.6 N.A. N.A. 33.3 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 23 0 12 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 12 12 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 0 0 0 0 0 0 0 0 0 0 12 12 % D
% Glu: 0 12 0 12 0 0 0 0 12 0 0 12 0 12 0 % E
% Phe: 0 0 0 12 0 12 0 0 0 12 0 0 0 0 0 % F
% Gly: 0 12 0 12 12 23 0 12 0 45 0 12 23 23 0 % G
% His: 0 12 0 12 0 0 0 12 0 0 0 0 12 34 12 % H
% Ile: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 23 0 23 0 0 0 0 0 45 12 12 0 12 0 0 % K
% Leu: 23 12 23 23 12 12 0 23 0 23 0 0 0 0 12 % L
% Met: 0 0 0 0 0 12 0 0 0 0 0 0 12 0 0 % M
% Asn: 12 0 0 0 12 0 12 12 0 0 12 0 12 0 0 % N
% Pro: 0 12 0 0 23 0 0 0 12 0 0 0 0 12 0 % P
% Gln: 0 0 0 0 12 0 0 0 0 0 0 23 0 0 12 % Q
% Arg: 34 0 34 0 12 0 12 0 12 12 56 34 12 12 34 % R
% Ser: 0 0 0 0 0 23 56 45 23 0 23 0 0 0 23 % S
% Thr: 0 0 0 0 0 12 12 0 0 0 0 0 0 0 0 % T
% Val: 12 23 0 12 0 0 0 0 0 0 0 12 0 0 0 % V
% Trp: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 0 0 0 0 0 12 23 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _