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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASTE1 All Species: 2.42
Human Site: Y606 Identified Species: 6.67
UniProt: Q2TB18 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TB18 NP_054784.2 679 77093 Y606 E A K Q L Y E Y L F N A T R S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001113246 520 58840 K451 L L E T L K V K Q T I L D P I
Dog Lupus familis XP_853344 461 52096 S392 S P H L E N T S W N V L P S Q
Cat Felis silvestris
Mouse Mus musculus Q8BIR2 672 76352 Q600 S L C P E A K Q L Y E H L F N
Rat Rattus norvegicus NP_001035246 672 76539 Q600 S I C P E A R Q L Y E H L F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514361 662 75505 T593 L L S T C P E T S H L Y N R L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LYL8 692 79210 Q589 S A E R I F K Q L K D I I V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VPW1 854 98358 W782 F Y C Y L Y D W C A E F I P T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792821 720 80781 S641 V P C R L F I S M H D F I T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 72.4 60.9 N.A. 78.1 79.2 N.A. 64.8 N.A. N.A. 35.9 N.A. 23 N.A. N.A. 30.2
Protein Similarity: 100 N.A. 75.1 64.5 N.A. 86.7 87 N.A. 77.6 N.A. N.A. 52.4 N.A. 37.7 N.A. N.A. 47.7
P-Site Identity: 100 N.A. 6.6 0 N.A. 6.6 13.3 N.A. 13.3 N.A. N.A. 20 N.A. 13.3 N.A. N.A. 13.3
P-Site Similarity: 100 N.A. 13.3 0 N.A. 26.6 20 N.A. 13.3 N.A. N.A. 60 N.A. 33.3 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 23 0 0 0 23 0 0 0 12 0 12 0 0 0 % A
% Cys: 0 0 45 0 12 0 0 0 12 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 12 0 0 0 23 0 12 0 0 % D
% Glu: 12 0 23 0 34 0 23 0 0 0 34 0 0 0 0 % E
% Phe: 12 0 0 0 0 23 0 0 0 12 0 23 0 23 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 12 0 0 0 0 0 0 23 0 23 0 0 0 % H
% Ile: 0 12 0 0 12 0 12 0 0 0 12 12 34 0 12 % I
% Lys: 0 0 12 0 0 12 23 12 0 12 0 0 0 0 0 % K
% Leu: 23 34 0 12 45 0 0 0 45 0 12 23 23 0 12 % L
% Met: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 12 0 0 0 12 12 0 12 0 12 % N
% Pro: 0 23 0 23 0 12 0 0 0 0 0 0 12 23 0 % P
% Gln: 0 0 0 12 0 0 0 34 12 0 0 0 0 0 12 % Q
% Arg: 0 0 0 23 0 0 12 0 0 0 0 0 0 23 0 % R
% Ser: 45 0 12 0 0 0 0 23 12 0 0 0 0 12 45 % S
% Thr: 0 0 0 23 0 0 12 12 0 12 0 0 12 12 12 % T
% Val: 12 0 0 0 0 0 12 0 0 0 12 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 12 12 0 0 0 0 0 0 % W
% Tyr: 0 12 0 12 0 23 0 12 0 23 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _