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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HKDC1
All Species:
25.45
Human Site:
Y740
Identified Species:
62.22
UniProt:
Q2TB90
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TB90
NP_079406.3
917
102515
Y740
L
N
P
G
K
Q
R
Y
E
K
M
T
S
G
M
Chimpanzee
Pan troglodytes
XP_001169069
971
108044
Y795
L
N
A
G
K
Q
R
Y
E
K
M
I
S
G
M
Rhesus Macaque
Macaca mulatta
XP_001110556
917
102399
Y740
L
N
P
G
K
Q
R
Y
E
K
M
T
S
G
M
Dog
Lupus familis
XP_546137
917
102633
Y740
L
N
P
G
K
Q
R
Y
E
K
M
T
S
G
M
Cat
Felis silvestris
Mouse
Mus musculus
Q91W97
915
102241
Y738
L
N
A
G
K
Q
R
Y
E
K
M
T
S
G
M
Rat
Rattus norvegicus
P05708
918
102389
F741
L
N
S
G
K
Q
R
F
E
K
M
I
S
G
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421579
917
102174
Y741
L
N
A
G
K
Q
R
Y
E
K
M
T
S
G
M
Frog
Xenopus laevis
NP_001096656
916
102431
Y741
L
N
S
G
K
Q
R
Y
E
K
M
I
S
G
M
Zebra Danio
Brachydanio rerio
NP_001108597
919
102529
F741
L
N
A
G
K
Q
R
F
E
K
M
T
S
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NFT7
486
53467
D334
L
V
R
L
V
I
T
D
M
I
A
K
G
F
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.9
99.1
93.5
N.A.
91.1
70
N.A.
N.A.
83.9
72.1
75
N.A.
23.1
N.A.
N.A.
N.A.
Protein Similarity:
100
80.3
99.6
97.5
N.A.
96.4
85.2
N.A.
N.A.
92.8
86.4
86.4
N.A.
35.4
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
100
100
N.A.
93.3
80
N.A.
N.A.
93.3
86.6
86.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
100
100
N.A.
93.3
86.6
N.A.
N.A.
93.3
86.6
93.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
40
0
0
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
90
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
20
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
90
0
0
0
0
0
0
0
0
10
90
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
10
0
30
0
0
0
% I
% Lys:
0
0
0
0
90
0
0
0
0
90
0
10
0
0
0
% K
% Leu:
100
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
90
0
0
0
100
% M
% Asn:
0
90
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
90
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
90
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
20
0
0
0
0
0
0
0
0
0
90
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
60
0
0
0
% T
% Val:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _