KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE4
All Species:
17.88
Human Site:
S211
Identified Species:
35.76
UniProt:
Q2TBC4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBC4
NP_037529.3
344
37551
S211
R
Y
S
D
A
G
S
S
W
A
G
A
L
E
G
Chimpanzee
Pan troglodytes
XP_518466
564
60722
S430
R
Y
S
D
A
G
S
S
W
A
G
A
L
E
G
Rhesus Macaque
Macaca mulatta
XP_001084780
385
41787
S251
R
Y
S
D
A
G
S
S
W
A
G
A
L
E
G
Dog
Lupus familis
XP_538916
439
47231
S311
R
Y
S
A
A
G
S
S
Q
A
P
A
L
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y24
845
95821
G459
S
S
S
M
A
L
K
G
H
G
G
S
F
I
Q
Rat
Rattus norvegicus
Q71QF9
831
94152
Q383
D
D
V
S
L
S
G
Q
G
A
G
F
A
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
T297
L
Y
A
E
Y
C
D
T
C
A
Q
H
I
G
I
Chicken
Gallus gallus
XP_001234704
864
97886
S352
N
G
S
D
S
S
D
S
A
F
Q
S
A
R
A
Frog
Xenopus laevis
Q90Z06
835
94992
G547
L
A
L
S
N
I
T
G
A
S
V
D
A
E
S
Zebra Danio
Brachydanio rerio
NP_001025269
872
99282
S563
L
S
N
I
T
G
A
S
V
D
G
D
S
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
L406
C
C
T
C
R
C
S
L
L
G
R
P
F
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
K450
K
E
T
L
H
I
A
K
D
S
R
T
D
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.4
83.9
56.4
N.A.
22.7
22.7
N.A.
22
22.3
22.8
22.2
N.A.
24.3
N.A.
N.A.
21.7
Protein Similarity:
100
60.8
85.1
63.3
N.A.
29.7
29.9
N.A.
29.3
29.2
30.1
28.6
N.A.
30.8
N.A.
N.A.
29.4
P-Site Identity:
100
100
100
80
N.A.
20
13.3
N.A.
13.3
20
6.6
20
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
80
N.A.
26.6
13.3
N.A.
40
33.3
20
40
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
42
0
17
0
17
50
0
34
25
0
9
% A
% Cys:
9
9
0
9
0
17
0
0
9
0
0
0
0
0
0
% C
% Asp:
9
9
0
34
0
0
17
0
9
9
0
17
9
0
9
% D
% Glu:
0
9
0
9
0
0
0
0
0
0
0
0
0
42
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
9
17
0
0
% F
% Gly:
0
9
0
0
0
42
9
17
9
17
50
0
0
9
34
% G
% His:
0
0
0
0
9
0
0
0
9
0
0
9
0
9
0
% H
% Ile:
0
0
0
9
0
17
0
0
0
0
0
0
9
9
9
% I
% Lys:
9
0
0
0
0
0
9
9
0
0
0
0
0
9
0
% K
% Leu:
25
0
9
9
9
9
0
9
9
0
0
0
34
9
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
9
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
9
9
0
17
0
0
0
9
% Q
% Arg:
34
0
0
0
9
0
0
0
0
0
17
0
0
9
0
% R
% Ser:
9
17
50
17
9
17
42
50
0
17
0
17
9
0
9
% S
% Thr:
0
0
17
0
9
0
9
9
0
0
0
9
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
9
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% W
% Tyr:
0
42
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _