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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRICKLE4 All Species: 39.09
Human Site: S308 Identified Species: 78.18
UniProt: Q2TBC4 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TBC4 NP_037529.3 344 37551 S308 T C S S S S D S E P E G F F L
Chimpanzee Pan troglodytes XP_518466 564 60722 S528 T C S S S S D S E P E G F F L
Rhesus Macaque Macaca mulatta XP_001084780 385 41787 S349 T C S S S S D S E P E G F F L
Dog Lupus familis XP_538916 439 47231 S403 T C S S S S D S E P E G F F L
Cat Felis silvestris
Mouse Mus musculus Q80Y24 845 95821 S785 T C S S S S E S D N E G Y F L
Rat Rattus norvegicus Q71QF9 831 94152 S772 S S T S S S D S E E E G Y F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508261 882 99961 S822 T C S S S S E S D N E G Y F L
Chicken Gallus gallus XP_001234704 864 97886 S804 T C S S S S E S D N E G Y F L
Frog Xenopus laevis Q90Z06 835 94992 S776 C S S S S S D S E E E G Y F L
Zebra Danio Brachydanio rerio NP_001025269 872 99282 S816 C S S S S S E S E E E G F F L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U1I1 785 86590 T687 L R L H N A Q T Q V G T T P L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194491 836 95332 R738 A D T Y H S E R G R D G Q Y G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.4 83.9 56.4 N.A. 22.7 22.7 N.A. 22 22.3 22.8 22.2 N.A. 24.3 N.A. N.A. 21.7
Protein Similarity: 100 60.8 85.1 63.3 N.A. 29.7 29.9 N.A. 29.3 29.2 30.1 28.6 N.A. 30.8 N.A. N.A. 29.4
P-Site Identity: 100 100 100 100 N.A. 73.3 66.6 N.A. 73.3 73.3 73.3 73.3 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 86.6 N.A. 93.3 93.3 80 80 N.A. 33.3 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % A
% Cys: 17 59 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 50 0 25 0 9 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 42 0 59 25 84 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 42 84 0 % F
% Gly: 0 0 0 0 0 0 0 0 9 0 9 92 0 0 9 % G
% His: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 92 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 25 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 34 0 0 0 9 0 % P
% Gln: 0 0 0 0 0 0 9 0 9 0 0 0 9 0 0 % Q
% Arg: 0 9 0 0 0 0 0 9 0 9 0 0 0 0 0 % R
% Ser: 9 25 75 84 84 92 0 84 0 0 0 0 0 0 0 % S
% Thr: 59 0 17 0 0 0 0 9 0 0 0 9 9 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 42 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _