KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE4
All Species:
4.24
Human Site:
T258
Identified Species:
8.48
UniProt:
Q2TBC4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBC4
NP_037529.3
344
37551
T258
A
G
G
S
S
L
Q
T
Q
R
G
L
P
G
S
Chimpanzee
Pan troglodytes
XP_518466
564
60722
Q477
A
A
G
G
S
S
L
Q
T
Q
R
G
L
P
G
Rhesus Macaque
Macaca mulatta
XP_001084780
385
41787
Q298
A
A
G
G
S
C
L
Q
T
Q
T
G
L
P
G
Dog
Lupus familis
XP_538916
439
47231
P358
E
A
R
R
G
P
L
P
S
S
P
E
Q
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y24
845
95821
E506
P
V
P
K
Y
E
E
E
E
E
E
E
E
G
G
Rat
Rattus norvegicus
Q71QF9
831
94152
Q430
G
D
K
N
L
F
Q
Q
P
P
S
E
V
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
I344
F
L
P
K
Q
G
Q
I
F
C
S
R
A
C
S
Chicken
Gallus gallus
XP_001234704
864
97886
L399
T
D
V
D
P
L
S
L
Q
M
D
L
L
S
L
Frog
Xenopus laevis
Q90Z06
835
94992
S594
M
L
N
R
S
T
E
S
L
K
S
L
N
S
E
Zebra Danio
Brachydanio rerio
NP_001025269
872
99282
S610
M
L
H
R
S
A
N
S
L
R
S
L
N
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
I453
R
A
S
T
S
S
Q
I
A
K
S
P
R
R
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
S497
S
K
D
M
S
R
R
S
L
P
D
L
R
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.4
83.9
56.4
N.A.
22.7
22.7
N.A.
22
22.3
22.8
22.2
N.A.
24.3
N.A.
N.A.
21.7
Protein Similarity:
100
60.8
85.1
63.3
N.A.
29.7
29.9
N.A.
29.3
29.2
30.1
28.6
N.A.
30.8
N.A.
N.A.
29.4
P-Site Identity:
100
20
20
0
N.A.
6.6
6.6
N.A.
13.3
20
13.3
20
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
26.6
0
N.A.
20
13.3
N.A.
13.3
20
33.3
26.6
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
34
0
0
0
9
0
0
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
9
0
0
0
9
0
% C
% Asp:
0
17
9
9
0
0
0
0
0
0
17
0
0
9
9
% D
% Glu:
9
0
0
0
0
9
17
9
9
9
9
25
9
9
17
% E
% Phe:
9
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% F
% Gly:
9
9
25
17
9
9
0
0
0
0
9
17
0
17
42
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% I
% Lys:
0
9
9
17
0
0
0
0
0
17
0
0
0
0
0
% K
% Leu:
0
25
0
0
9
17
25
9
25
0
0
42
25
0
9
% L
% Met:
17
0
0
9
0
0
0
0
0
9
0
0
0
0
9
% M
% Asn:
0
0
9
9
0
0
9
0
0
0
0
0
17
9
0
% N
% Pro:
9
0
17
0
9
9
0
9
9
17
9
9
9
17
0
% P
% Gln:
0
0
0
0
9
0
34
25
17
17
0
0
9
0
0
% Q
% Arg:
9
0
9
25
0
9
9
0
0
17
9
9
17
9
0
% R
% Ser:
9
0
9
9
59
17
9
25
9
9
42
0
0
25
17
% S
% Thr:
9
0
0
9
0
9
0
9
17
0
9
0
0
0
0
% T
% Val:
0
9
9
0
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _