KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE4
All Species:
11.21
Human Site:
T290
Identified Species:
22.42
UniProt:
Q2TBC4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBC4
NP_037529.3
344
37551
T290
Q
E
Q
C
R
L
E
T
I
R
D
P
K
D
T
Chimpanzee
Pan troglodytes
XP_518466
564
60722
T510
Q
E
Q
C
R
L
E
T
I
R
D
P
K
D
T
Rhesus Macaque
Macaca mulatta
XP_001084780
385
41787
T331
Q
E
Q
C
R
L
E
T
L
C
D
S
K
D
T
Dog
Lupus familis
XP_538916
439
47231
P385
E
R
G
R
L
E
K
P
L
D
A
R
E
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y24
845
95821
G767
N
A
F
G
E
R
W
G
P
Y
F
T
E
Y
D
Rat
Rattus norvegicus
Q71QF9
831
94152
L754
G
M
T
R
F
L
G
L
Y
G
D
D
D
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
R804
N
A
F
G
E
R
W
R
P
Y
F
A
E
Y
D
Chicken
Gallus gallus
XP_001234704
864
97886
G786
N
H
L
G
E
R
W
G
P
Y
F
A
E
Y
D
Frog
Xenopus laevis
Q90Z06
835
94992
Y758
V
D
K
F
L
G
L
Y
G
E
D
E
D
S
W
Zebra Danio
Brachydanio rerio
NP_001025269
872
99282
D798
D
Q
F
Q
D
F
C
D
D
D
E
E
D
D
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
S669
R
R
R
N
Q
S
R
S
S
S
E
M
Q
I
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
M720
K
R
R
P
N
E
H
M
S
R
S
A
S
H
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.4
83.9
56.4
N.A.
22.7
22.7
N.A.
22
22.3
22.8
22.2
N.A.
24.3
N.A.
N.A.
21.7
Protein Similarity:
100
60.8
85.1
63.3
N.A.
29.7
29.9
N.A.
29.3
29.2
30.1
28.6
N.A.
30.8
N.A.
N.A.
29.4
P-Site Identity:
100
100
80
6.6
N.A.
0
20
N.A.
0
0
6.6
6.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
86.6
33.3
N.A.
6.6
26.6
N.A.
6.6
6.6
20
20
N.A.
40
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
0
0
0
0
0
0
9
25
0
0
9
% A
% Cys:
0
0
0
25
0
0
9
0
0
9
0
0
0
0
0
% C
% Asp:
9
9
0
0
9
0
0
9
9
17
42
9
25
50
25
% D
% Glu:
9
25
0
0
25
17
25
0
0
9
17
17
34
0
0
% E
% Phe:
0
0
25
9
9
9
0
0
0
0
25
0
0
0
9
% F
% Gly:
9
0
9
25
0
9
9
17
9
9
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
9
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
17
0
0
0
0
9
0
% I
% Lys:
9
0
9
0
0
0
9
0
0
0
0
0
25
0
0
% K
% Leu:
0
0
9
0
17
34
9
9
17
0
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
9
0
0
0
9
0
0
0
% M
% Asn:
25
0
0
9
9
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
9
0
0
0
9
25
0
0
17
0
0
0
% P
% Gln:
25
9
25
9
9
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
9
25
17
17
25
25
9
9
0
25
0
9
0
0
0
% R
% Ser:
0
0
0
0
0
9
0
9
17
9
9
9
9
9
9
% S
% Thr:
0
0
9
0
0
0
0
25
0
0
0
9
0
0
25
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
17
% W
% Tyr:
0
0
0
0
0
0
0
9
9
25
0
0
0
25
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _