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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE4
All Species:
9.7
Human Site:
T325
Identified Species:
19.39
UniProt:
Q2TBC4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBC4
NP_037529.3
344
37551
T325
R
L
P
Q
S
W
K
T
P
G
S
L
Q
A
E
Chimpanzee
Pan troglodytes
XP_518466
564
60722
T545
R
L
P
Q
S
W
K
T
P
G
S
L
Q
A
E
Rhesus Macaque
Macaca mulatta
XP_001084780
385
41787
I366
R
L
P
L
S
W
K
I
L
G
S
L
Q
A
E
Dog
Lupus familis
XP_538916
439
47231
S420
R
L
P
G
P
W
K
S
P
G
S
L
Q
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y24
845
95821
L802
P
I
P
Q
P
A
R
L
R
Y
V
T
S
D
E
Rat
Rattus norvegicus
Q71QF9
831
94152
Q789
P
I
P
Q
P
R
P
Q
R
F
T
Y
Y
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
L839
P
I
P
Q
P
A
R
L
R
Y
V
T
S
E
E
Chicken
Gallus gallus
XP_001234704
864
97886
L821
P
I
P
Q
P
A
R
L
Q
Y
V
T
S
E
E
Frog
Xenopus laevis
Q90Z06
835
94992
Q793
P
I
P
K
P
R
P
Q
R
Y
Q
Y
F
S
D
Zebra Danio
Brachydanio rerio
NP_001025269
872
99282
Q833
P
I
P
K
P
R
S
Q
S
F
H
Y
Y
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
D704
L
N
N
L
D
N
C
D
V
A
S
I
C
S
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
S755
R
M
T
R
T
V
S
S
H
M
K
Y
D
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.4
83.9
56.4
N.A.
22.7
22.7
N.A.
22
22.3
22.8
22.2
N.A.
24.3
N.A.
N.A.
21.7
Protein Similarity:
100
60.8
85.1
63.3
N.A.
29.7
29.9
N.A.
29.3
29.2
30.1
28.6
N.A.
30.8
N.A.
N.A.
29.4
P-Site Identity:
100
100
80
73.3
N.A.
20
13.3
N.A.
20
20
6.6
13.3
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
80
80
N.A.
33.3
33.3
N.A.
33.3
33.3
33.3
26.6
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
25
0
0
0
9
0
0
0
34
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
9
0
0
9
0
0
0
0
9
9
17
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
59
% E
% Phe:
0
0
0
0
0
0
0
0
0
17
0
0
9
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
34
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% H
% Ile:
0
50
0
0
0
0
0
9
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
17
0
0
34
0
0
0
9
0
0
9
0
% K
% Leu:
9
34
0
17
0
0
0
25
9
0
0
34
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
9
9
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
50
0
84
0
59
0
17
0
25
0
0
0
0
0
0
% P
% Gln:
0
0
0
50
0
0
0
25
9
0
9
0
34
0
0
% Q
% Arg:
42
0
0
9
0
25
25
0
34
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
25
0
17
17
9
0
42
0
25
17
0
% S
% Thr:
0
0
9
0
9
0
0
17
0
0
9
25
0
17
9
% T
% Val:
0
0
0
0
0
9
0
0
9
0
25
0
0
0
0
% V
% Trp:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
34
0
34
17
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _