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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWF19L2
All Species:
16.06
Human Site:
S137
Identified Species:
29.44
UniProt:
Q2TBE0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBE0
NULL
890
103397
S137
W
K
V
K
D
E
K
S
G
K
D
D
T
Q
I
Chimpanzee
Pan troglodytes
XP_522171
894
103894
S141
W
K
V
K
D
E
K
S
E
K
D
D
T
Q
I
Rhesus Macaque
Macaca mulatta
XP_001102590
893
103520
S140
W
K
M
K
D
E
K
S
E
K
D
D
T
Q
I
Dog
Lupus familis
XP_536589
889
102949
S137
W
K
V
K
D
E
N
S
E
R
E
D
N
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG79
887
103154
T137
W
K
V
K
D
K
R
T
E
E
E
C
D
S
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508889
876
100906
W122
G
V
V
E
R
D
E
W
M
T
L
D
F
M
S
Chicken
Gallus gallus
XP_417167
1001
114241
S247
A
W
K
V
S
K
Q
S
D
A
A
K
E
P
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q3LSS0
960
110552
P138
E
G
E
P
E
A
T
P
S
S
S
S
A
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXT5
687
78130
Honey Bee
Apis mellifera
XP_001122298
596
70639
Nematode Worm
Caenorhab. elegans
Q10946
460
53149
Sea Urchin
Strong. purpuratus
XP_001198735
730
82866
R39
N
A
E
K
E
K
E
R
E
K
T
K
N
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564716
692
79178
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
95.5
85.1
N.A.
73.7
N.A.
N.A.
64.7
53.3
N.A.
49.6
N.A.
29.2
29.5
24.9
33.1
Protein Similarity:
100
98.6
97.3
92
N.A.
84.9
N.A.
N.A.
78
67
N.A.
67.2
N.A.
45.3
45.7
36.8
50.7
P-Site Identity:
100
93.3
86.6
60
N.A.
33.3
N.A.
N.A.
13.3
6.6
N.A.
0
N.A.
0
0
0
13.3
P-Site Similarity:
100
93.3
93.3
80
N.A.
66.6
N.A.
N.A.
33.3
20
N.A.
6.6
N.A.
0
0
0
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
0
0
0
8
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
39
8
0
0
8
0
24
39
8
0
0
% D
% Glu:
8
0
16
8
16
31
16
0
39
8
16
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% I
% Lys:
0
39
8
47
0
24
24
0
0
31
0
16
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
0
0
8
0
0
0
0
0
16
0
8
% N
% Pro:
0
0
0
8
0
0
0
8
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
31
0
% Q
% Arg:
0
0
0
0
8
0
8
8
0
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
39
8
8
8
8
0
16
16
% S
% Thr:
0
0
0
0
0
0
8
8
0
8
8
0
24
0
0
% T
% Val:
0
8
39
8
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
39
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _