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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CWF19L2 All Species: 10.61
Human Site: S309 Identified Species: 19.44
UniProt: Q2TBE0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TBE0 NULL 890 103397 S309 D L V K Y G N S S R D R Y A T
Chimpanzee Pan troglodytes XP_522171 894 103894 S313 D L V K Y G N S S R D R Y A T
Rhesus Macaque Macaca mulatta XP_001102590 893 103520 S312 D L V K Y D N S S R D R Y A T
Dog Lupus familis XP_536589 889 102949 N309 D L V K Y N K N S R D R Y H S
Cat Felis silvestris
Mouse Mus musculus Q8BG79 887 103154 L309 D L V K C K N L S E D R H L E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508889 876 100906 D294 R D Y S R D R D K R M Y V A R
Chicken Gallus gallus XP_417167 1001 114241 R419 E T R H E D G R N M S G G H A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q3LSS0 960 110552 E310 R E R W R R D E E K D R W R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXT5 687 78130 S169 S L L L K T F S R E R K E P A
Honey Bee Apis mellifera XP_001122298 596 70639 S78 E D W M N I K S I L P C V F N
Nematode Worm Caenorhab. elegans Q10946 460 53149
Sea Urchin Strong. purpuratus XP_001198735 730 82866 R211 S R R D S T S R G F R R P G E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564716 692 79178 L174 A A R E G L R L E E V A G E R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 95.5 85.1 N.A. 73.7 N.A. N.A. 64.7 53.3 N.A. 49.6 N.A. 29.2 29.5 24.9 33.1
Protein Similarity: 100 98.6 97.3 92 N.A. 84.9 N.A. N.A. 78 67 N.A. 67.2 N.A. 45.3 45.7 36.8 50.7
P-Site Identity: 100 100 93.3 66.6 N.A. 53.3 N.A. N.A. 13.3 0 N.A. 13.3 N.A. 13.3 6.6 0 6.6
P-Site Similarity: 100 100 93.3 80 N.A. 60 N.A. N.A. 13.3 13.3 N.A. 33.3 N.A. 26.6 13.3 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. 29.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 0 0 0 0 0 8 0 31 16 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 39 16 0 8 0 24 8 8 0 0 47 0 0 0 0 % D
% Glu: 16 8 0 8 8 0 0 8 16 24 0 0 8 8 16 % E
% Phe: 0 0 0 0 0 0 8 0 0 8 0 0 0 8 0 % F
% Gly: 0 0 0 0 8 16 8 0 8 0 0 8 16 8 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 8 16 0 % H
% Ile: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 0 39 8 8 16 0 8 8 0 8 0 0 0 % K
% Leu: 0 47 8 8 0 8 0 16 0 8 0 0 0 8 0 % L
% Met: 0 0 0 8 0 0 0 0 0 8 8 0 0 0 0 % M
% Asn: 0 0 0 0 8 8 31 8 8 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 0 8 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 16 8 31 0 16 8 16 16 8 39 16 54 0 8 24 % R
% Ser: 16 0 0 8 8 0 8 39 39 0 8 0 0 0 8 % S
% Thr: 0 8 0 0 0 16 0 0 0 0 0 0 0 0 24 % T
% Val: 0 0 39 0 0 0 0 0 0 0 8 0 16 0 0 % V
% Trp: 0 0 8 8 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 8 0 31 0 0 0 0 0 0 8 31 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _