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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWF19L2
All Species:
21.52
Human Site:
S374
Identified Species:
39.44
UniProt:
Q2TBE0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBE0
NULL
890
103397
S374
P
S
D
D
E
E
L
S
F
H
S
K
G
R
K
Chimpanzee
Pan troglodytes
XP_522171
894
103894
S378
P
S
D
D
E
E
L
S
F
H
S
K
G
R
K
Rhesus Macaque
Macaca mulatta
XP_001102590
893
103520
S377
P
S
D
D
E
E
L
S
F
H
S
K
G
R
T
Dog
Lupus familis
XP_536589
889
102949
S375
P
S
D
D
E
E
L
S
F
H
S
K
G
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG79
887
103154
F373
S
D
E
D
E
L
S
F
H
K
R
K
N
F
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508889
876
100906
S363
K
P
S
D
D
E
E
S
A
L
R
S
G
S
R
Chicken
Gallus gallus
XP_417167
1001
114241
S487
K
P
S
E
D
D
L
S
S
Y
S
A
S
G
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q3LSS0
960
110552
S385
P
S
E
D
E
E
V
S
R
G
A
G
F
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXT5
687
78130
S233
S
S
S
S
A
Q
G
S
S
R
G
W
R
K
P
Honey Bee
Apis mellifera
XP_001122298
596
70639
K142
K
I
D
I
N
W
L
K
K
G
L
Q
R
A
K
Nematode Worm
Caenorhab. elegans
Q10946
460
53149
Sea Urchin
Strong. purpuratus
XP_001198735
730
82866
Q275
K
R
P
G
D
E
R
Q
D
S
R
S
S
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564716
692
79178
L238
K
G
N
N
R
E
Y
L
K
G
E
S
L
N
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
95.5
85.1
N.A.
73.7
N.A.
N.A.
64.7
53.3
N.A.
49.6
N.A.
29.2
29.5
24.9
33.1
Protein Similarity:
100
98.6
97.3
92
N.A.
84.9
N.A.
N.A.
78
67
N.A.
67.2
N.A.
45.3
45.7
36.8
50.7
P-Site Identity:
100
100
93.3
93.3
N.A.
20
N.A.
N.A.
26.6
20
N.A.
46.6
N.A.
13.3
20
0
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
33.3
N.A.
N.A.
40
46.6
N.A.
73.3
N.A.
26.6
26.6
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
39
54
24
8
0
0
8
0
0
0
0
0
8
% D
% Glu:
0
0
16
8
47
62
8
0
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
31
0
0
0
8
8
0
% F
% Gly:
0
8
0
8
0
0
8
0
0
24
8
8
39
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
31
0
0
0
0
8
% H
% Ile:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
39
0
0
0
0
0
0
8
16
8
0
39
0
16
31
% K
% Leu:
0
0
0
0
0
8
47
8
0
8
8
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
8
0
0
0
0
0
0
0
8
8
8
% N
% Pro:
39
16
8
0
0
0
0
0
0
0
0
0
0
8
8
% P
% Gln:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% Q
% Arg:
0
8
0
0
8
0
8
0
8
8
24
0
16
31
8
% R
% Ser:
16
47
24
8
0
0
8
62
16
8
39
24
16
8
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _