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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWF19L2
All Species:
15.15
Human Site:
S399
Identified Species:
27.78
UniProt:
Q2TBE0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBE0
NULL
890
103397
S399
V
A
Q
G
S
L
C
S
G
F
R
K
P
T
K
Chimpanzee
Pan troglodytes
XP_522171
894
103894
S403
V
A
Q
G
S
L
C
S
G
F
R
K
P
T
K
Rhesus Macaque
Macaca mulatta
XP_001102590
893
103520
S402
V
A
Q
G
S
L
R
S
G
F
R
K
P
T
E
Dog
Lupus familis
XP_536589
889
102949
P400
V
D
H
G
F
R
K
P
T
E
N
S
E
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG79
887
103154
F398
Q
A
S
L
H
C
D
F
R
K
L
T
E
N
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508889
876
100906
S388
S
A
Q
S
A
L
R
S
G
F
R
K
P
T
E
Chicken
Gallus gallus
XP_417167
1001
114241
S512
P
H
H
S
S
L
S
S
R
F
Q
K
P
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q3LSS0
960
110552
E410
R
K
P
V
D
D
V
E
M
S
R
E
A
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXT5
687
78130
A258
S
R
S
R
S
K
S
A
T
S
S
D
E
E
E
Honey Bee
Apis mellifera
XP_001122298
596
70639
W167
K
D
I
V
A
E
R
W
G
S
L
E
M
I
E
Nematode Worm
Caenorhab. elegans
Q10946
460
53149
L31
A
E
K
Y
A
K
K
L
G
S
E
F
S
T
G
Sea Urchin
Strong. purpuratus
XP_001198735
730
82866
R300
E
E
L
D
K
D
D
R
H
S
R
G
G
H
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564716
692
79178
K263
S
L
S
W
G
K
R
K
S
Q
T
H
R
N
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
95.5
85.1
N.A.
73.7
N.A.
N.A.
64.7
53.3
N.A.
49.6
N.A.
29.2
29.5
24.9
33.1
Protein Similarity:
100
98.6
97.3
92
N.A.
84.9
N.A.
N.A.
78
67
N.A.
67.2
N.A.
45.3
45.7
36.8
50.7
P-Site Identity:
100
100
86.6
13.3
N.A.
6.6
N.A.
N.A.
66.6
40
N.A.
6.6
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
100
93.3
13.3
N.A.
6.6
N.A.
N.A.
80
60
N.A.
13.3
N.A.
20
26.6
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
39
0
0
24
0
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
8
16
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
8
8
16
16
0
0
0
0
8
0
0
0
% D
% Glu:
8
16
0
0
0
8
0
8
0
8
8
16
24
16
47
% E
% Phe:
0
0
0
0
8
0
0
8
0
39
0
8
0
0
8
% F
% Gly:
0
0
0
31
8
0
0
0
47
0
0
8
8
8
8
% G
% His:
0
8
16
0
8
0
0
0
8
0
0
8
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
8
8
8
0
8
24
16
8
0
8
0
39
0
0
16
% K
% Leu:
0
8
8
8
0
39
0
8
0
0
16
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
16
0
% N
% Pro:
8
0
8
0
0
0
0
8
0
0
0
0
39
0
0
% P
% Gln:
8
0
31
0
0
0
0
0
0
8
8
0
0
0
0
% Q
% Arg:
8
8
0
8
0
8
31
8
16
0
47
0
8
0
0
% R
% Ser:
24
0
24
16
39
0
16
39
8
39
8
8
8
8
24
% S
% Thr:
0
0
0
0
0
0
0
0
16
0
8
8
0
39
0
% T
% Val:
31
0
0
16
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _