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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWF19L2
All Species:
10.91
Human Site:
S450
Identified Species:
20
UniProt:
Q2TBE0
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBE0
NULL
890
103397
S450
P
E
D
P
R
E
K
S
Q
D
E
V
L
R
D
Chimpanzee
Pan troglodytes
XP_522171
894
103894
S454
P
E
D
P
R
E
K
S
Q
D
E
V
L
R
D
Rhesus Macaque
Macaca mulatta
XP_001102590
893
103520
S453
P
E
D
T
R
E
K
S
Q
D
E
D
L
R
G
Dog
Lupus familis
XP_536589
889
102949
E451
A
R
E
E
S
R
D
E
S
L
R
D
D
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG79
887
103154
L449
T
G
G
R
R
E
Q
L
Q
A
E
S
M
S
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508889
876
100906
E439
A
R
Q
K
S
E
G
E
N
L
R
G
I
P
E
Chicken
Gallus gallus
XP_417167
1001
114241
R563
S
F
E
K
E
K
S
R
E
E
Y
P
T
S
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q3LSS0
960
110552
G461
A
F
R
K
P
V
D
G
D
H
D
D
D
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXT5
687
78130
Q309
L
A
A
E
L
N
Q
Q
L
E
A
A
R
K
E
Honey Bee
Apis mellifera
XP_001122298
596
70639
V218
N
K
L
G
A
K
I
V
K
A
E
I
M
G
N
Nematode Worm
Caenorhab. elegans
Q10946
460
53149
S82
E
D
E
K
N
K
L
S
A
K
I
L
K
A
E
Sea Urchin
Strong. purpuratus
XP_001198735
730
82866
S351
D
V
G
S
S
G
S
S
S
P
D
T
K
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564716
692
79178
R314
V
E
T
R
G
D
H
R
S
D
V
E
Q
E
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
95.5
85.1
N.A.
73.7
N.A.
N.A.
64.7
53.3
N.A.
49.6
N.A.
29.2
29.5
24.9
33.1
Protein Similarity:
100
98.6
97.3
92
N.A.
84.9
N.A.
N.A.
78
67
N.A.
67.2
N.A.
45.3
45.7
36.8
50.7
P-Site Identity:
100
100
80
0
N.A.
26.6
N.A.
N.A.
6.6
0
N.A.
0
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
100
80
6.6
N.A.
40
N.A.
N.A.
20
26.6
N.A.
6.6
N.A.
26.6
46.6
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
8
0
8
0
0
0
8
16
8
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
8
24
0
0
8
16
0
8
31
16
24
16
0
16
% D
% Glu:
8
31
24
16
8
39
0
16
8
16
39
8
0
24
31
% E
% Phe:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
16
8
8
8
8
8
0
0
0
8
0
8
8
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
8
8
8
0
8
% I
% Lys:
0
8
0
31
0
24
24
0
8
8
0
0
16
8
0
% K
% Leu:
8
0
8
0
8
0
8
8
8
16
0
8
24
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
8
% M
% Asn:
8
0
0
0
8
8
0
0
8
0
0
0
0
0
8
% N
% Pro:
24
0
0
16
8
0
0
0
0
8
0
8
0
8
0
% P
% Gln:
0
0
8
0
0
0
16
8
31
0
0
0
8
0
0
% Q
% Arg:
0
16
8
16
31
8
0
16
0
0
16
0
8
24
0
% R
% Ser:
8
0
0
8
24
0
16
39
24
0
0
8
0
24
0
% S
% Thr:
8
0
8
8
0
0
0
0
0
0
0
8
8
0
0
% T
% Val:
8
8
0
0
0
8
0
8
0
0
8
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _