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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CWF19L2 All Species: 10
Human Site: S475 Identified Species: 18.33
UniProt: Q2TBE0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TBE0 NULL 890 103397 S475 T K S T F A G S P E R E S I H
Chimpanzee Pan troglodytes XP_522171 894 103894 S479 T K S T F A G S P E H E S I H
Rhesus Macaque Macaca mulatta XP_001102590 893 103520 S478 T K S T F A G S P E H E S I H
Dog Lupus familis XP_536589 889 102949 G474 L S P F A G G G P E D D S S H
Cat Felis silvestris
Mouse Mus musculus Q8BG79 887 103154 G473 D M T L T I A G P E A E S T Y
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508889 876 100906 A462 K P L L P G G A S E D E P T Q
Chicken Gallus gallus XP_417167 1001 114241 H587 S M T S C S R H P S E D E P P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q3LSS0 960 110552 E543 T V S S S E S E E E E E E E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXT5 687 78130 N331 G E S V R N A N T R P A K S K
Honey Bee Apis mellifera XP_001122298 596 70639 R240 K M Q L Q K A R E I I Q N T Q
Nematode Worm Caenorhab. elegans Q10946 460 53149 L104 V K K L K R K L E S G I S G D
Sea Urchin Strong. purpuratus XP_001198735 730 82866 P373 E K D K S P S P V K L L S D I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564716 692 79178 S336 D D E G T L P S M E N L S V N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 95.5 85.1 N.A. 73.7 N.A. N.A. 64.7 53.3 N.A. 49.6 N.A. 29.2 29.5 24.9 33.1
Protein Similarity: 100 98.6 97.3 92 N.A. 84.9 N.A. N.A. 78 67 N.A. 67.2 N.A. 45.3 45.7 36.8 50.7
P-Site Identity: 100 93.3 93.3 33.3 N.A. 26.6 N.A. N.A. 20 6.6 N.A. 26.6 N.A. 6.6 0 13.3 13.3
P-Site Similarity: 100 93.3 93.3 40 N.A. 40 N.A. N.A. 26.6 40 N.A. 33.3 N.A. 20 13.3 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. 29.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 24 24 8 0 0 8 8 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 8 8 0 0 0 0 0 0 0 16 16 0 8 8 % D
% Glu: 8 8 8 0 0 8 0 8 24 62 16 47 16 8 0 % E
% Phe: 0 0 0 8 24 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 8 0 16 39 16 0 0 8 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 16 0 0 0 31 % H
% Ile: 0 0 0 0 0 8 0 0 0 8 8 8 0 24 8 % I
% Lys: 16 39 8 8 8 8 8 0 0 8 0 0 8 0 8 % K
% Leu: 8 0 8 31 0 8 0 8 0 0 8 16 0 0 8 % L
% Met: 0 24 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 0 8 0 8 0 8 % N
% Pro: 0 8 8 0 8 8 8 8 47 0 8 0 8 8 8 % P
% Gln: 0 0 8 0 8 0 0 0 0 0 0 8 0 0 16 % Q
% Arg: 0 0 0 0 8 8 8 8 0 8 8 0 0 0 0 % R
% Ser: 8 8 39 16 16 8 16 31 8 16 0 0 62 16 0 % S
% Thr: 31 0 16 24 16 0 0 0 8 0 0 0 0 24 0 % T
% Val: 8 8 0 8 0 0 0 0 8 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _