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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CWF19L2 All Species: 13.94
Human Site: T436 Identified Species: 25.56
UniProt: Q2TBE0 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TBE0 NULL 890 103397 T436 Q K P S E T S T D E H Q H V P
Chimpanzee Pan troglodytes XP_522171 894 103894 T440 Q K P S E T S T D E Y Q H V P
Rhesus Macaque Macaca mulatta XP_001102590 893 103520 T439 Q K P L E T S T D E Y Q H V P
Dog Lupus familis XP_536589 889 102949 H437 E T G G T V D H G N V S D N A
Cat Felis silvestris
Mouse Mus musculus Q8BG79 887 103154 Y435 K P L E T W S Y N A N Q H S T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508889 876 100906 R425 Q K V L S G S R G E I P K D A
Chicken Gallus gallus XP_417167 1001 114241 N549 S L D T A A K N D G E R T Q S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q3LSS0 960 110552 S447 G T A F K K G S S S N Q S A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXT5 687 78130 E295 A G K A I K A E L K G K K E L
Honey Bee Apis mellifera XP_001122298 596 70639 P204 D V N I E T K P L T E A E M N
Nematode Worm Caenorhab. elegans Q10946 460 53149 S68 D V M K S S D S G G A P L T E
Sea Urchin Strong. purpuratus XP_001198735 730 82866 S337 R S G R R S D S E E E N S D D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564716 692 79178 K300 K E M L S K Q K N V S V S P V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 95.5 85.1 N.A. 73.7 N.A. N.A. 64.7 53.3 N.A. 49.6 N.A. 29.2 29.5 24.9 33.1
Protein Similarity: 100 98.6 97.3 92 N.A. 84.9 N.A. N.A. 78 67 N.A. 67.2 N.A. 45.3 45.7 36.8 50.7
P-Site Identity: 100 93.3 86.6 0 N.A. 20 N.A. N.A. 26.6 6.6 N.A. 6.6 N.A. 0 13.3 0 6.6
P-Site Similarity: 100 100 93.3 6.6 N.A. 40 N.A. N.A. 26.6 20 N.A. 26.6 N.A. 26.6 20 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 29.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 8 8 8 0 0 8 8 8 0 8 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 0 8 0 0 0 24 0 31 0 0 0 8 16 8 % D
% Glu: 8 8 0 8 31 0 0 8 8 39 24 0 8 8 8 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 16 8 0 8 8 0 24 16 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 8 0 31 0 0 % H
% Ile: 0 0 0 8 8 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 16 31 8 8 8 24 16 8 0 8 0 8 16 0 0 % K
% Leu: 0 8 8 24 0 0 0 0 16 0 0 0 8 0 8 % L
% Met: 0 0 16 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 8 0 0 0 0 8 16 8 16 8 0 8 8 % N
% Pro: 0 8 24 0 0 0 0 8 0 0 0 16 0 8 24 % P
% Gln: 31 0 0 0 0 0 8 0 0 0 0 39 0 8 0 % Q
% Arg: 8 0 0 8 8 0 0 8 0 0 0 8 0 0 0 % R
% Ser: 8 8 0 16 24 16 39 24 8 8 8 8 24 8 8 % S
% Thr: 0 16 0 8 16 31 0 24 0 8 0 0 8 8 8 % T
% Val: 0 16 8 0 0 8 0 0 0 8 8 8 0 24 8 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 16 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _