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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWF19L2
All Species:
22.42
Human Site:
Y197
Identified Species:
41.11
UniProt:
Q2TBE0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBE0
NULL
890
103397
Y197
M
E
R
E
L
N
P
Y
W
K
D
G
G
T
G
Chimpanzee
Pan troglodytes
XP_522171
894
103894
Y201
M
E
R
E
L
N
P
Y
W
K
D
G
G
T
G
Rhesus Macaque
Macaca mulatta
XP_001102590
893
103520
Y200
M
E
R
E
L
N
P
Y
W
K
D
G
G
T
G
Dog
Lupus familis
XP_536589
889
102949
Y197
L
E
R
E
L
N
P
Y
W
K
D
G
G
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG79
887
103154
P197
L
L
E
R
E
L
N
P
Y
W
K
D
G
G
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508889
876
100906
H182
T
G
L
P
P
E
E
H
V
S
S
V
A
K
V
Chicken
Gallus gallus
XP_417167
1001
114241
Y307
S
E
R
E
L
N
P
Y
W
K
D
G
G
T
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q3LSS0
960
110552
Y198
H
R
L
E
L
N
P
Y
W
K
D
G
G
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXT5
687
78130
L57
A
D
W
M
L
P
A
L
A
K
K
L
E
K
P
Honey Bee
Apis mellifera
XP_001122298
596
70639
Nematode Worm
Caenorhab. elegans
Q10946
460
53149
Sea Urchin
Strong. purpuratus
XP_001198735
730
82866
Y99
V
S
W
L
K
K
S
Y
Q
R
A
V
E
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564716
692
79178
E62
I
A
K
S
G
D
G
E
T
V
D
D
D
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
95.5
85.1
N.A.
73.7
N.A.
N.A.
64.7
53.3
N.A.
49.6
N.A.
29.2
29.5
24.9
33.1
Protein Similarity:
100
98.6
97.3
92
N.A.
84.9
N.A.
N.A.
78
67
N.A.
67.2
N.A.
45.3
45.7
36.8
50.7
P-Site Identity:
100
100
100
93.3
N.A.
6.6
N.A.
N.A.
0
93.3
N.A.
73.3
N.A.
13.3
0
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
20
N.A.
N.A.
6.6
93.3
N.A.
80
N.A.
20
0
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
8
0
8
0
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
8
0
0
0
0
54
16
8
0
0
% D
% Glu:
0
39
8
47
8
8
8
8
0
0
0
0
16
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
0
8
0
0
0
0
47
54
8
47
% G
% His:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
8
8
0
0
0
54
16
0
0
16
0
% K
% Leu:
16
8
16
8
54
8
0
8
0
0
0
8
0
8
8
% L
% Met:
24
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
47
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
8
8
47
8
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% Q
% Arg:
0
8
39
8
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
8
0
8
0
0
8
0
0
8
8
0
0
8
0
% S
% Thr:
8
0
0
0
0
0
0
0
8
0
0
0
0
39
8
% T
% Val:
8
0
0
0
0
0
0
0
8
8
0
16
0
0
8
% V
% Trp:
0
0
16
0
0
0
0
0
47
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _