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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWF19L2
All Species:
10
Human Site:
Y278
Identified Species:
18.33
UniProt:
Q2TBE0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBE0
NULL
890
103397
Y278
A
A
S
T
K
E
D
Y
R
R
E
R
W
R
K
Chimpanzee
Pan troglodytes
XP_522171
894
103894
Y282
A
A
S
T
K
E
D
Y
R
R
E
R
W
R
K
Rhesus Macaque
Macaca mulatta
XP_001102590
893
103520
Y281
A
A
S
T
R
E
D
Y
R
R
E
R
W
R
K
Dog
Lupus familis
XP_536589
889
102949
C278
T
A
S
T
K
E
D
C
K
R
E
R
W
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG79
887
103154
C278
I
A
Y
K
K
E
D
C
G
W
E
R
W
R
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508889
876
100906
S263
K
P
R
D
G
D
P
S
G
W
E
K
Q
E
G
Chicken
Gallus gallus
XP_417167
1001
114241
D388
V
A
P
K
K
E
N
D
Y
R
S
G
R
W
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q3LSS0
960
110552
D279
A
A
Y
G
E
R
R
D
D
E
K
E
R
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXT5
687
78130
P138
E
D
E
W
V
E
A
P
P
P
L
A
A
D
N
Honey Bee
Apis mellifera
XP_001122298
596
70639
P47
E
Q
E
W
I
E
K
P
I
C
E
R
T
F
K
Nematode Worm
Caenorhab. elegans
Q10946
460
53149
Sea Urchin
Strong. purpuratus
XP_001198735
730
82866
K180
D
G
R
R
D
D
E
K
E
R
R
K
D
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564716
692
79178
L143
K
H
G
K
D
Q
L
L
P
S
S
V
V
G
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
95.5
85.1
N.A.
73.7
N.A.
N.A.
64.7
53.3
N.A.
49.6
N.A.
29.2
29.5
24.9
33.1
Protein Similarity:
100
98.6
97.3
92
N.A.
84.9
N.A.
N.A.
78
67
N.A.
67.2
N.A.
45.3
45.7
36.8
50.7
P-Site Identity:
100
100
93.3
80
N.A.
60
N.A.
N.A.
6.6
33.3
N.A.
13.3
N.A.
6.6
26.6
0
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
60
N.A.
N.A.
20
40
N.A.
33.3
N.A.
6.6
26.6
0
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
54
0
0
0
0
8
0
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
16
0
8
0
0
0
0
0
% C
% Asp:
8
8
0
8
16
16
39
16
8
0
0
0
8
16
8
% D
% Glu:
16
0
16
0
8
62
8
0
8
8
54
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
8
8
8
0
0
0
16
0
0
8
0
16
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
16
0
0
24
39
0
8
8
8
0
8
16
0
0
54
% K
% Leu:
0
0
0
0
0
0
8
8
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
0
8
8
0
0
0
8
16
16
8
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
16
8
8
8
8
0
24
47
8
47
16
39
16
% R
% Ser:
0
0
31
0
0
0
0
8
0
8
16
0
0
0
0
% S
% Thr:
8
0
0
31
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
8
0
0
0
8
0
0
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
16
0
0
0
0
0
16
0
0
39
8
0
% W
% Tyr:
0
0
16
0
0
0
0
24
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _