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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWF19L2
All Species:
21.52
Human Site:
Y629
Identified Species:
39.44
UniProt:
Q2TBE0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TBE0
NULL
890
103397
Y629
M
G
K
T
D
G
D
Y
Y
T
L
D
D
M
F
Chimpanzee
Pan troglodytes
XP_522171
894
103894
Y633
M
G
K
T
D
G
D
Y
Y
T
L
D
D
M
F
Rhesus Macaque
Macaca mulatta
XP_001102590
893
103520
Y632
M
G
K
T
D
G
D
Y
Y
T
L
D
D
M
F
Dog
Lupus familis
XP_536589
889
102949
Y628
M
G
K
T
D
G
D
Y
Y
T
L
D
D
M
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG79
887
103154
N626
M
G
K
S
D
E
D
N
Y
T
L
D
D
M
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508889
876
100906
Y616
M
E
K
T
D
R
E
Y
Y
T
L
D
D
M
F
Chicken
Gallus gallus
XP_417167
1001
114241
Y741
M
E
K
T
D
R
D
Y
Y
T
L
D
D
M
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q3LSS0
960
110552
N700
M
G
R
T
D
G
D
N
Y
T
L
D
D
M
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXT5
687
78130
R461
R
E
M
Q
S
A
I
R
E
H
E
K
L
V
A
Honey Bee
Apis mellifera
XP_001122298
596
70639
L370
A
I
K
E
H
E
H
L
S
K
S
L
D
N
C
Nematode Worm
Caenorhab. elegans
Q10946
460
53149
R234
K
E
H
K
R
I
E
R
S
F
D
D
C
S
R
Sea Urchin
Strong. purpuratus
XP_001198735
730
82866
A503
A
D
H
Q
H
T
V
A
R
L
S
K
C
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564716
692
79178
Q466
R
V
K
R
I
M
T
Q
Q
E
R
C
L
F
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
95.5
85.1
N.A.
73.7
N.A.
N.A.
64.7
53.3
N.A.
49.6
N.A.
29.2
29.5
24.9
33.1
Protein Similarity:
100
98.6
97.3
92
N.A.
84.9
N.A.
N.A.
78
67
N.A.
67.2
N.A.
45.3
45.7
36.8
50.7
P-Site Identity:
100
100
100
100
N.A.
80
N.A.
N.A.
80
86.6
N.A.
86.6
N.A.
0
13.3
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
86.6
86.6
N.A.
93.3
N.A.
6.6
13.3
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
16
0
16
% C
% Asp:
0
8
0
0
62
0
54
0
0
0
8
70
70
0
0
% D
% Glu:
0
31
0
8
0
16
16
0
8
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
70
% F
% Gly:
0
47
0
0
0
39
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
16
0
16
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
8
8
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
70
8
0
0
0
0
0
8
0
16
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
8
62
8
16
0
0
% L
% Met:
62
0
8
0
0
8
0
0
0
0
0
0
0
62
0
% M
% Asn:
0
0
0
0
0
0
0
16
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
16
0
0
0
8
8
0
0
0
0
0
0
% Q
% Arg:
16
0
8
8
8
16
0
16
8
0
8
0
0
0
8
% R
% Ser:
0
0
0
8
8
0
0
0
16
0
16
0
0
16
0
% S
% Thr:
0
0
0
54
0
8
8
0
0
62
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
8
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
62
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _