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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4B All Species: 16.36
Human Site: S1113 Identified Species: 24
UniProt: Q2VIQ3 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2VIQ3 NP_001092763.1 1234 140035 S1113 S D C G V D C S C D P T K C R
Chimpanzee Pan troglodytes XP_518055 1227 139177 S1106 S D C G V D C S C D P T K C R
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 C1113 S D C G V D C C C D P T K C R
Dog Lupus familis XP_549061 1234 139874 S1113 S D C G M D C S C D S T K C R
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 S1111 S D C N V S C S C D P T K C R
Rat Rattus norvegicus Q7M6Z5 1394 158861 T1195 D G E G I I E T L N K Y E D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 G1103 G C R K Q K V G C T A G C S C
Frog Xenopus laevis Q91784 1226 138905 D1107 T K Q N C S D D C F C D P S K
Zebra Danio Brachydanio rerio Q58G59 1363 154819 C1236 V N L T G E Q C K G L N C D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 E665 N I V N Y E L E M P C R T T Q
Honey Bee Apis mellifera XP_395595 1064 123475 L941 P D W K R T P L Y N R V Q S L
Nematode Worm Caenorhab. elegans P46873 699 78760 I580 N E D E S R W I L P E M S M S
Sea Urchin Strong. purpuratus P46872 699 78679 S580 L E N V R E L S R E L R L S M
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 A927 A V A L A T A A S A G Q E Q R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200901 1294 145204 C1062 S D V C C C T C S K S S S C K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 S809 R Q L V E Q N S A L K K E V A
Conservation
Percent
Protein Identity: 100 97.9 90.9 91 N.A. 83.6 26.4 N.A. N.A. 71.3 66.6 25.1 N.A. 27.2 36.8 25.6 27.4
Protein Similarity: 100 98.8 94 94.7 N.A. 90.3 47.2 N.A. N.A. 83.7 80.1 44.1 N.A. 41 55.8 38.5 38.4
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 6.6 N.A. N.A. 6.6 6.6 0 N.A. 0 6.6 0 6.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 40 N.A. N.A. 6.6 20 13.3 N.A. 20 20 13.3 26.6
Percent
Protein Identity: 31.9 N.A. N.A. 30.6 N.A. 26.6
Protein Similarity: 50 N.A. N.A. 49.1 N.A. 44
P-Site Identity: 6.6 N.A. N.A. 20 N.A. 6.6
P-Site Similarity: 26.6 N.A. N.A. 33.3 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 7 0 7 7 7 7 7 0 0 0 7 % A
% Cys: 0 7 32 7 13 7 32 19 44 0 13 0 13 38 7 % C
% Asp: 7 44 7 0 0 25 7 7 0 32 0 7 0 13 0 % D
% Glu: 0 13 7 7 7 19 7 7 0 7 7 0 19 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % F
% Gly: 7 7 0 32 7 0 0 7 0 7 7 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 7 7 0 7 0 0 0 0 0 0 0 % I
% Lys: 0 7 0 13 0 7 0 0 7 7 13 7 32 0 19 % K
% Leu: 7 0 13 7 0 0 13 7 13 7 13 0 7 0 7 % L
% Met: 0 0 0 0 7 0 0 0 7 0 0 7 0 7 7 % M
% Asn: 13 7 7 19 0 0 7 0 0 13 0 7 0 0 0 % N
% Pro: 7 0 0 0 0 0 7 0 0 13 25 0 7 0 0 % P
% Gln: 0 7 7 0 7 7 7 0 0 0 0 7 7 7 7 % Q
% Arg: 7 0 7 0 13 7 0 0 7 0 7 13 0 0 38 % R
% Ser: 38 0 0 0 7 13 0 38 13 0 13 7 13 25 13 % S
% Thr: 7 0 0 7 0 13 7 7 0 7 0 32 7 7 0 % T
% Val: 7 7 13 13 25 0 7 0 0 0 0 7 0 7 0 % V
% Trp: 0 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 7 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _