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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4B All Species: 7.27
Human Site: S1195 Identified Species: 10.67
UniProt: Q2VIQ3 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2VIQ3 NP_001092763.1 1234 140035 S1195 S P F D L P E S K H G A T E Y
Chimpanzee Pan troglodytes XP_518055 1227 139177 S1188 S P F D L P E S K H G A T E Y
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 L1195 S L F D L P E L K H V A T E Y
Dog Lupus familis XP_549061 1234 139874 L1195 S S F G L L E L K H V A T E S
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 K1193 S S D H P E L K S I A S E S Q
Rat Rattus norvegicus Q7M6Z5 1394 158861 K1277 T K L N G R E K E V D N S S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 L1185 K P S T A A S L L V R D E E S
Frog Xenopus laevis Q91784 1226 138905 S1189 S T A S A S A S V M E S Q E N
Zebra Danio Brachydanio rerio Q58G59 1363 154819 G1318 N N R I V Q P G M N S T H W S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 G747 R N I K S S R G L P S A A S N
Honey Bee Apis mellifera XP_395595 1064 123475 E1023 F V E N I E E E R E K C D E L
Nematode Worm Caenorhab. elegans P46873 699 78760 S662 T S K S L F P S K T P T F D G
Sea Urchin Strong. purpuratus P46872 699 78679 K662 N L E G G G M K Y K P S Q G K
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 W1009 Q G G K L W R W K R S H H Q W
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200901 1294 145204 A1144 G A M L L Q N A L A D K P E E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 L891 G S R I A K P L R G G G D A V
Conservation
Percent
Protein Identity: 100 97.9 90.9 91 N.A. 83.6 26.4 N.A. N.A. 71.3 66.6 25.1 N.A. 27.2 36.8 25.6 27.4
Protein Similarity: 100 98.8 94 94.7 N.A. 90.3 47.2 N.A. N.A. 83.7 80.1 44.1 N.A. 41 55.8 38.5 38.4
P-Site Identity: 100 100 80 60 N.A. 6.6 6.6 N.A. N.A. 13.3 20 0 N.A. 6.6 13.3 20 0
P-Site Similarity: 100 100 80 60 N.A. 13.3 33.3 N.A. N.A. 13.3 26.6 20 N.A. 6.6 33.3 33.3 13.3
Percent
Protein Identity: 31.9 N.A. N.A. 30.6 N.A. 26.6
Protein Similarity: 50 N.A. N.A. 49.1 N.A. 44
P-Site Identity: 13.3 N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: 26.6 N.A. N.A. 20 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 19 7 7 7 0 7 7 32 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 7 19 0 0 0 0 0 0 13 7 13 7 0 % D
% Glu: 0 0 13 0 0 13 38 7 7 7 7 0 13 50 7 % E
% Phe: 7 0 25 0 0 7 0 0 0 0 0 0 7 0 0 % F
% Gly: 13 7 7 13 13 7 0 13 0 7 19 7 0 7 7 % G
% His: 0 0 0 7 0 0 0 0 0 25 0 7 13 0 0 % H
% Ile: 0 0 7 13 7 0 0 0 0 7 0 0 0 0 0 % I
% Lys: 7 7 7 13 0 7 0 19 38 7 7 7 0 0 7 % K
% Leu: 0 13 7 7 44 7 7 25 19 0 0 0 0 0 7 % L
% Met: 0 0 7 0 0 0 7 0 7 7 0 0 0 0 0 % M
% Asn: 13 13 0 13 0 0 7 0 0 7 0 7 0 0 13 % N
% Pro: 0 19 0 0 7 19 19 0 0 7 13 0 7 0 0 % P
% Gln: 7 0 0 0 0 13 0 0 0 0 0 0 13 7 7 % Q
% Arg: 7 0 13 0 0 7 13 0 13 7 7 0 0 0 0 % R
% Ser: 38 25 7 13 7 13 7 25 7 0 19 19 7 19 25 % S
% Thr: 13 7 0 7 0 0 0 0 0 7 0 13 25 0 0 % T
% Val: 0 7 0 0 7 0 0 0 7 13 13 0 0 0 7 % V
% Trp: 0 0 0 0 0 7 0 7 0 0 0 0 0 7 7 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _