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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF2S3L
All Species:
0
Human Site:
S104
Identified Species:
0
UniProt:
Q2VIR3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2VIR3
NP_001406
472
51229
S104
P
R
P
E
C
Y
R
S
C
G
S
S
M
P
D
Chimpanzee
Pan troglodytes
XP_001149413
472
51278
Rhesus Macaque
Macaca mulatta
XP_001089902
472
51065
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0N1
472
51047
Rat
Rattus norvegicus
P81795
472
51061
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513184
390
42538
Chicken
Gallus gallus
Q5ZMS3
472
51058
Frog
Xenopus laevis
NP_001080565
472
51279
Zebra Danio
Brachydanio rerio
NP_997876
472
51302
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24208
475
51466
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490960
469
51216
Sea Urchin
Strong. purpuratus
XP_001178408
448
48596
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32481
527
57847
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.3
N.A.
N.A.
98
98.3
N.A.
80.5
97.2
95.7
95.1
N.A.
79.5
N.A.
72.6
82.2
Protein Similarity:
100
99.5
98.9
N.A.
N.A.
98.7
98.9
N.A.
81.3
98
97.2
97
N.A.
86.5
N.A.
83
86.6
P-Site Identity:
100
0
0
N.A.
N.A.
0
0
N.A.
0
0
0
0
N.A.
0
N.A.
0
0
P-Site Similarity:
100
0
0
N.A.
N.A.
0
0
N.A.
0
0
0
0
N.A.
0
N.A.
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
63.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
75.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
100
0
0
0
100
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% D
% Glu:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
100
0
100
0
0
0
0
0
0
0
0
0
0
100
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
100
0
0
0
0
100
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
100
100
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _