KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRTG
All Species:
35.45
Human Site:
T614
Identified Species:
86.67
UniProt:
Q2VWP7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2VWP7
NP_776175.2
1150
127076
T614
S
H
R
T
P
K
A
T
S
V
K
A
P
K
S
Chimpanzee
Pan troglodytes
XP_510430
1150
127041
T614
S
H
R
T
P
K
A
T
S
V
K
A
P
K
S
Rhesus Macaque
Macaca mulatta
XP_001090352
1150
126879
T614
S
H
R
T
P
K
A
T
S
V
K
A
P
K
S
Dog
Lupus familis
XP_544694
1474
161427
T888
S
H
R
T
P
K
A
T
S
V
K
A
P
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q2EY15
1191
130515
T608
S
H
R
T
P
K
A
T
S
V
K
A
P
K
S
Rat
Rattus norvegicus
Q2VWP9
1193
131061
T609
S
H
R
T
P
K
A
T
S
V
K
A
P
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514305
1188
130286
T602
S
H
R
T
P
K
A
T
S
V
K
A
P
K
S
Chicken
Gallus gallus
Q589G5
1187
130497
T606
S
H
R
T
P
K
A
T
S
V
K
A
P
K
S
Frog
Xenopus laevis
Q90Z04
1249
137058
D601
L
M
W
R
S
G
K
D
G
G
L
P
I
N
A
Zebra Danio
Brachydanio rerio
Q2EY14
1149
126278
S601
S
H
R
T
P
K
A
S
S
T
K
V
P
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.4
74.9
N.A.
87.3
87
N.A.
85.2
82.2
20.5
61.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.9
99.3
76.5
N.A.
91.8
90.9
N.A.
90.7
89.2
37.1
75.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
0
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
6.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
90
0
0
0
0
80
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
10
10
0
0
0
0
0
% G
% His:
0
90
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
90
10
0
0
0
90
0
0
80
0
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
90
0
0
0
0
0
0
10
90
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
90
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
90
0
0
0
10
0
0
10
90
0
0
0
0
0
80
% S
% Thr:
0
0
0
90
0
0
0
80
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
80
0
10
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _