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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LETM2
All Species:
11.21
Human Site:
S252
Identified Species:
27.41
UniProt:
Q2VYF4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2VYF4
NP_653253.1
491
55921
S252
R
A
K
M
G
D
A
S
T
Q
L
S
S
Y
V
Chimpanzee
Pan troglodytes
XP_001171298
444
50543
Q216
S
S
Y
V
K
Q
V
Q
T
G
H
K
P
S
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532802
593
66182
Q346
S
S
Y
V
K
Q
V
Q
T
G
H
K
P
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNU7
480
54440
S250
R
A
K
L
G
D
A
S
S
Q
L
S
S
Y
V
Rat
Rattus norvegicus
Q5PQQ5
459
52505
L226
K
K
M
M
G
A
K
L
E
I
A
K
F
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZK33
752
85831
T280
K
A
A
K
G
N
V
T
K
D
F
S
T
F
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LY46
757
86828
T290
K
A
S
K
G
N
V
T
E
E
F
S
T
F
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91927
1013
113562
A311
K
E
H
S
S
E
E
A
K
Q
F
E
A
F
F
Honey Bee
Apis mellifera
XP_624231
764
87758
A247
T
D
C
K
S
Q
K
A
K
E
F
A
E
F
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781116
544
61879
S313
I
E
E
T
A
L
Q
S
K
K
G
S
S
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.2
N.A.
46.7
N.A.
77.5
73.1
N.A.
N.A.
33.6
N.A.
31.9
N.A.
23.3
28.1
N.A.
37.5
Protein Similarity:
100
89.6
N.A.
56.6
N.A.
83.3
79.4
N.A.
N.A.
46.5
N.A.
47.1
N.A.
33.1
41.3
N.A.
55.1
P-Site Identity:
100
6.6
N.A.
6.6
N.A.
86.6
13.3
N.A.
N.A.
20
N.A.
20
N.A.
6.6
0
N.A.
20
P-Site Similarity:
100
20
N.A.
20
N.A.
100
20
N.A.
N.A.
53.3
N.A.
60
N.A.
40
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
10
0
10
10
20
20
0
0
10
10
10
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
20
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
20
10
0
0
10
10
0
20
20
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
40
0
10
40
40
% F
% Gly:
0
0
0
0
50
0
0
0
0
20
10
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
20
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
40
10
20
30
20
0
20
0
40
10
0
30
0
0
0
% K
% Leu:
0
0
0
10
0
10
0
10
0
0
20
0
0
10
0
% L
% Met:
0
0
10
20
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% P
% Gln:
0
0
0
0
0
30
10
20
0
30
0
0
0
0
20
% Q
% Arg:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
20
10
10
20
0
0
30
10
0
0
50
30
30
0
% S
% Thr:
10
0
0
10
0
0
0
20
30
0
0
0
20
0
20
% T
% Val:
0
0
0
20
0
0
40
0
0
0
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
0
0
0
0
0
0
0
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _