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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LETM2
All Species:
20.3
Human Site:
S322
Identified Species:
49.63
UniProt:
Q2VYF4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2VYF4
NP_653253.1
491
55921
S322
Q
L
L
M
K
L
K
S
I
K
A
D
D
E
I
Chimpanzee
Pan troglodytes
XP_001171298
444
50543
S275
Q
L
L
M
K
L
K
S
I
K
A
D
D
E
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532802
593
66182
S405
Q
L
L
M
K
L
K
S
I
K
A
D
D
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNU7
480
54440
R311
F
G
T
N
N
L
L
R
F
Q
L
L
M
T
L
Rat
Rattus norvegicus
Q5PQQ5
459
52505
H290
E
D
Q
L
A
L
E
H
L
R
R
P
Q
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZK33
752
85831
T351
Q
L
T
M
R
L
R
T
I
K
A
D
D
K
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LY46
757
86828
A361
Q
L
I
M
K
L
R
A
I
R
A
D
D
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91927
1013
113562
S382
Q
L
R
L
K
L
R
S
L
A
T
D
D
R
V
Honey Bee
Apis mellifera
XP_624231
764
87758
S318
L
L
R
M
R
L
R
S
L
T
A
D
D
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781116
544
61879
L372
Q
L
R
A
L
S
R
L
L
Q
L
N
T
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.2
N.A.
46.7
N.A.
77.5
73.1
N.A.
N.A.
33.6
N.A.
31.9
N.A.
23.3
28.1
N.A.
37.5
Protein Similarity:
100
89.6
N.A.
56.6
N.A.
83.3
79.4
N.A.
N.A.
46.5
N.A.
47.1
N.A.
33.1
41.3
N.A.
55.1
P-Site Identity:
100
100
N.A.
93.3
N.A.
6.6
6.6
N.A.
N.A.
60
N.A.
60
N.A.
46.6
46.6
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
20
46.6
N.A.
N.A.
93.3
N.A.
100
N.A.
73.3
80
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
0
10
0
10
60
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
70
70
0
0
% D
% Glu:
10
0
0
0
0
0
10
0
0
0
0
0
0
30
0
% E
% Phe:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
50
0
0
0
0
10
20
% I
% Lys:
0
0
0
0
50
0
30
0
0
40
0
0
0
30
0
% K
% Leu:
10
80
30
20
10
90
10
10
40
0
20
10
0
10
30
% L
% Met:
0
0
0
60
0
0
0
0
0
0
0
0
10
0
10
% M
% Asn:
0
0
0
10
10
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
70
0
10
0
0
0
0
0
0
20
0
0
10
0
0
% Q
% Arg:
0
0
30
0
20
0
50
10
0
20
10
0
0
10
0
% R
% Ser:
0
0
0
0
0
10
0
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
20
0
0
0
0
10
0
10
10
0
10
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _