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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LETM2
All Species:
13.33
Human Site:
S404
Identified Species:
32.59
UniProt:
Q2VYF4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2VYF4
NP_653253.1
491
55921
S404
K
P
I
E
I
P
L
S
G
E
A
P
K
T
D
Chimpanzee
Pan troglodytes
XP_001171298
444
50543
S357
K
P
I
E
I
P
L
S
G
E
A
P
K
T
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532802
593
66182
S487
K
P
I
E
I
P
L
S
G
E
S
P
I
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNU7
480
54440
K393
T
F
Y
L
I
D
V
K
P
K
P
I
E
L
P
Rat
Rattus norvegicus
Q5PQQ5
459
52505
L372
R
Q
Q
L
T
E
W
L
D
L
H
L
K
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZK33
752
85831
T433
P
A
D
Q
L
K
T
T
L
Q
T
L
P
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LY46
757
86828
T443
P
A
D
Q
L
K
T
T
L
Q
N
L
P
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91927
1013
113562
T464
T
T
D
K
L
K
E
T
I
R
V
L
P
D
A
Honey Bee
Apis mellifera
XP_624231
764
87758
T400
M
S
D
K
L
K
A
T
I
S
A
L
P
D
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781116
544
61879
L454
D
E
Q
I
P
T
S
L
L
L
L
S
R
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.2
N.A.
46.7
N.A.
77.5
73.1
N.A.
N.A.
33.6
N.A.
31.9
N.A.
23.3
28.1
N.A.
37.5
Protein Similarity:
100
89.6
N.A.
56.6
N.A.
83.3
79.4
N.A.
N.A.
46.5
N.A.
47.1
N.A.
33.1
41.3
N.A.
55.1
P-Site Identity:
100
100
N.A.
86.6
N.A.
6.6
6.6
N.A.
N.A.
0
N.A.
0
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
26.6
20
N.A.
N.A.
26.6
N.A.
26.6
N.A.
20
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
0
10
0
0
0
30
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
40
0
0
10
0
0
10
0
0
0
0
20
30
% D
% Glu:
0
10
0
30
0
10
10
0
0
30
0
0
10
30
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
30
10
40
0
0
0
20
0
0
10
10
0
10
% I
% Lys:
30
0
0
20
0
40
0
10
0
10
0
0
30
0
0
% K
% Leu:
0
0
0
20
40
0
30
20
30
20
10
50
0
10
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% N
% Pro:
20
30
0
0
10
30
0
0
10
0
10
30
40
0
10
% P
% Gln:
0
10
20
20
0
0
0
0
0
20
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% R
% Ser:
0
10
0
0
0
0
10
30
0
10
10
10
0
0
10
% S
% Thr:
20
10
0
0
10
10
20
40
0
0
10
0
0
30
10
% T
% Val:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _