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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LETM2
All Species:
11.52
Human Site:
S477
Identified Species:
28.15
UniProt:
Q2VYF4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2VYF4
NP_653253.1
491
55921
S477
E
P
T
L
Q
A
K
S
Q
M
T
A
Q
N
S
Chimpanzee
Pan troglodytes
XP_001171298
444
50543
S430
E
P
T
L
Q
A
K
S
Q
M
T
A
Q
N
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532802
593
66182
K560
A
P
A
Q
S
L
G
K
F
V
G
D
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNU7
480
54440
S466
E
A
I
L
Q
A
K
S
Q
E
T
S
Q
N
S
Rat
Rattus norvegicus
Q5PQQ5
459
52505
S445
T
K
I
L
Q
A
K
S
Q
E
T
S
Q
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZK33
752
85831
A506
A
A
M
K
L
E
S
A
V
D
L
E
P
A
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LY46
757
86828
V516
Q
E
A
E
V
L
E
V
E
G
E
R
R
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91927
1013
113562
G537
V
F
A
E
K
L
S
G
S
Q
D
L
L
D
H
Honey Bee
Apis mellifera
XP_624231
764
87758
A473
D
V
K
V
L
E
Q
A
L
D
C
L
G
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781116
544
61879
E527
K
E
E
K
K
L
R
E
E
Q
E
L
L
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.2
N.A.
46.7
N.A.
77.5
73.1
N.A.
N.A.
33.6
N.A.
31.9
N.A.
23.3
28.1
N.A.
37.5
Protein Similarity:
100
89.6
N.A.
56.6
N.A.
83.3
79.4
N.A.
N.A.
46.5
N.A.
47.1
N.A.
33.1
41.3
N.A.
55.1
P-Site Identity:
100
100
N.A.
13.3
N.A.
73.3
66.6
N.A.
N.A.
0
N.A.
0
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
N.A.
26.6
N.A.
80
73.3
N.A.
N.A.
6.6
N.A.
26.6
N.A.
13.3
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
30
0
0
40
0
20
0
0
0
20
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
20
10
10
0
20
20
% D
% Glu:
30
20
10
20
0
20
10
10
20
20
20
10
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
10
0
10
10
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
10
20
20
0
40
10
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
40
20
40
0
0
10
0
10
30
30
0
10
% L
% Met:
0
0
10
0
0
0
0
0
0
20
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
40
0
% N
% Pro:
0
30
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
10
0
0
10
40
0
10
0
40
20
0
0
40
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
10
10
0
0
% R
% Ser:
0
0
0
0
10
0
20
40
10
0
0
20
0
10
50
% S
% Thr:
10
0
20
0
0
0
0
0
0
0
40
0
0
0
0
% T
% Val:
10
10
0
10
10
0
0
10
10
10
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _