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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LETM2 All Species: 5.76
Human Site: T46 Identified Species: 14.07
UniProt: Q2VYF4 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2VYF4 NP_653253.1 491 55921 T46 P D S H L N K T C M K N Y E S
Chimpanzee Pan troglodytes XP_001171298 444 50543 Q48 P G K P Q L E Q A T K H P Q V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532802 593 66182 T177 K D S H L S K T Y M K N Y V S
Cat Felis silvestris
Mouse Mus musculus Q7TNU7 480 54440 Y46 D S H L R T A Y I K N C G S R
Rat Rattus norvegicus Q5PQQ5 459 52505 Y46 D S H L R T A Y M K N C G S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZK33 752 85831 R74 C W T K G L E R T Y F T L M S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LY46 757 86828 A83 R S P R L Y C A I L V P D P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91927 1013 113562 T93 R H L H T S R T L L E T S S S
Honey Bee Apis mellifera XP_624231 764 87758 H46 K N N R L L L H S T I T E N Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781116 544 61879 H113 P T L L E P H H V Y A Q V I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.2 N.A. 46.7 N.A. 77.5 73.1 N.A. N.A. 33.6 N.A. 31.9 N.A. 23.3 28.1 N.A. 37.5
Protein Similarity: 100 89.6 N.A. 56.6 N.A. 83.3 79.4 N.A. N.A. 46.5 N.A. 47.1 N.A. 33.1 41.3 N.A. 55.1
P-Site Identity: 100 13.3 N.A. 73.3 N.A. 0 0 N.A. N.A. 6.6 N.A. 6.6 N.A. 20 6.6 N.A. 13.3
P-Site Similarity: 100 33.3 N.A. 80 N.A. 0 0 N.A. N.A. 20 N.A. 20 N.A. 46.6 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 20 10 10 0 10 0 0 0 10 % A
% Cys: 10 0 0 0 0 0 10 0 10 0 0 20 0 0 0 % C
% Asp: 20 20 0 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 0 0 10 0 20 0 0 0 10 0 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 10 0 0 10 0 0 0 0 0 0 0 20 0 0 % G
% His: 0 10 20 30 0 0 10 20 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 20 0 10 0 0 10 0 % I
% Lys: 20 0 10 10 0 0 20 0 0 20 30 0 0 0 0 % K
% Leu: 0 0 20 30 40 30 10 0 10 20 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 20 0 0 0 10 0 % M
% Asn: 0 10 10 0 0 10 0 0 0 0 20 20 0 10 0 % N
% Pro: 30 0 10 10 0 10 0 0 0 0 0 10 10 10 0 % P
% Gln: 0 0 0 0 10 0 0 10 0 0 0 10 0 10 0 % Q
% Arg: 20 0 0 20 20 0 10 10 0 0 0 0 0 0 20 % R
% Ser: 0 30 20 0 0 20 0 0 10 0 0 0 10 30 50 % S
% Thr: 0 10 10 0 10 20 0 30 10 20 0 30 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 10 0 10 10 10 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 20 10 20 0 0 20 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _