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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAB4 All Species: 1.21
Human Site: S169 Identified Species: 2.96
UniProt: Q2WGN9 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2WGN9 NP_001032903.1 574 62367 S169 L G N I S S A S H G L C S S P
Chimpanzee Pan troglodytes XP_525517 686 74573 H280 S L S K P S Q H N T E F R G S
Rhesus Macaque Macaca mulatta XP_001093686 561 61716 R157 S Q H L L R E R K S S A P S H
Dog Lupus familis XP_542285 762 83533 S348 H N T E F R D S T Y D L P R S
Cat Felis silvestris
Mouse Mus musculus Q9Z1S8 665 73190 P251 G F Y S L P K P S R H N T E F
Rat Rattus norvegicus Q9EQH1 665 73310 P251 G F Y S L P K P S R H N T E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513247 815 89872 A226 P G A L P A S A E L P L A I N
Chicken Gallus gallus XP_001234549 681 75233 L267 F R D S A Y D L P R S F G S Y
Frog Xenopus laevis NP_001089201 691 76011 Y232 Q K H A V N G Y F Q Q S S V Y
Zebra Danio Brachydanio rerio XP_692935 666 73590 P255 P G K H Q Q P P S R T D S Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.7 61.8 45.7 N.A. 51.4 51.2 N.A. 26.8 45.2 29.3 27.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 80.7 72.6 54.4 N.A. 61.6 61.6 N.A. 39.5 57.5 46 41.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 6.6 N.A. 0 0 N.A. 6.6 6.6 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 20 6.6 N.A. 6.6 6.6 N.A. 40 20 20 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 10 10 10 10 0 0 0 10 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 10 0 0 0 20 0 0 0 10 10 0 0 0 % D
% Glu: 0 0 0 10 0 0 10 0 10 0 10 0 0 20 10 % E
% Phe: 10 20 0 0 10 0 0 0 10 0 0 20 0 0 20 % F
% Gly: 20 30 0 0 0 0 10 0 0 10 0 0 10 10 0 % G
% His: 10 0 20 10 0 0 0 10 10 0 20 0 0 0 10 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 10 10 10 0 0 20 0 10 0 0 0 0 0 0 % K
% Leu: 10 10 0 20 30 0 0 10 0 10 10 20 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 10 0 0 10 0 0 10 0 0 20 0 0 10 % N
% Pro: 20 0 0 0 20 20 10 30 10 0 10 0 20 0 10 % P
% Gln: 10 10 0 0 10 10 10 0 0 10 10 0 0 10 0 % Q
% Arg: 0 10 0 0 0 20 0 10 0 40 0 0 10 10 0 % R
% Ser: 20 0 10 30 10 20 10 20 30 10 20 10 30 30 20 % S
% Thr: 0 0 10 0 0 0 0 0 10 10 10 0 20 0 0 % T
% Val: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 20 0 0 10 0 10 0 10 0 0 0 0 20 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _