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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANO4 All Species: 22.12
Human Site: S86 Identified Species: 48.67
UniProt: Q32M45 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q32M45 NP_849148.2 955 111462 S86 L H P G N L T S T S D D A S R
Chimpanzee Pan troglodytes XP_509302 955 111457 S86 L H P G N L T S T S D D A S R
Rhesus Macaque Macaca mulatta XP_001090523 955 111458 S86 L H P G N L T S T S D D A S R
Dog Lupus familis XP_854987 931 108790 V77 L E A G G E T V P E K N K S N
Cat Felis silvestris
Mouse Mus musculus Q8C5H1 955 111525 S86 L H P G N L T S T S E D T S R
Rat Rattus norvegicus Q6IFT6 860 97152 R66 L V W E E D L R S R E N P T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506513 1182 136128 S313 L H P G N L T S T S D D A S R
Chicken Gallus gallus XP_425452 976 114472 S107 L H H G N L T S T S D D A S R
Frog Xenopus laevis NP_001086810 896 105149 R84 A E K K A E R R R D F E F N L
Zebra Danio Brachydanio rerio Q4V8U5 646 74505
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001073009 921 106692 G77 N D L F F K D G K R R I D F V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.7 94.6 N.A. 98.3 35.7 N.A. 77.5 88.7 43.9 24.5 N.A. N.A. N.A. N.A. 42.9
Protein Similarity: 100 100 99.9 95.8 N.A. 99 53.6 N.A. 79.2 92.6 62.6 39.6 N.A. N.A. N.A. N.A. 61.2
P-Site Identity: 100 100 100 26.6 N.A. 86.6 6.6 N.A. 100 93.3 0 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 33.3 N.A. 93.3 40 N.A. 100 93.3 13.3 0 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 10 0 0 0 0 0 0 0 46 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 10 10 0 0 10 46 55 10 0 0 % D
% Glu: 0 19 0 10 10 19 0 0 0 10 19 10 0 0 0 % E
% Phe: 0 0 0 10 10 0 0 0 0 0 10 0 10 10 0 % F
% Gly: 0 0 0 64 10 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 55 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 10 10 0 10 0 0 10 0 10 0 10 0 0 % K
% Leu: 73 0 10 0 0 55 10 0 0 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 55 0 0 0 0 0 0 19 0 10 10 % N
% Pro: 0 0 46 0 0 0 0 0 10 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 10 19 10 19 10 0 0 0 55 % R
% Ser: 0 0 0 0 0 0 0 55 10 55 0 0 0 64 0 % S
% Thr: 0 0 0 0 0 0 64 0 55 0 0 0 10 10 0 % T
% Val: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 10 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _