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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANO4 All Species: 29.09
Human Site: Y805 Identified Species: 64
UniProt: Q32M45 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q32M45 NP_849148.2 955 111462 Y805 R L V Y A Y K Y G P C A G Q G
Chimpanzee Pan troglodytes XP_509302 955 111457 Y805 R L V Y A Y K Y G P C A G Q G
Rhesus Macaque Macaca mulatta XP_001090523 955 111458 Y805 R L V Y A Y K Y G P C A G Q G
Dog Lupus familis XP_854987 931 108790 Y781 R L V Y A Y K Y G P C A G Q G
Cat Felis silvestris
Mouse Mus musculus Q8C5H1 955 111525 Y805 R L V Y A Y K Y G P C A G Q G
Rat Rattus norvegicus Q6IFT6 860 97152 N747 P D L R G F L N F T L A R A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506513 1182 136128 Y1032 R L V Y A Y K Y G P C A G Q G
Chicken Gallus gallus XP_425452 976 114472 Y826 R L V Y A Y K Y G P C A G Q G
Frog Xenopus laevis NP_001086810 896 105149 M781 S M P T K N D M N V L S C R Y
Zebra Danio Brachydanio rerio Q4V8U5 646 74505 A534 I T E V Y S D A F K M C H V F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001073009 921 106692 Y770 R Q V F K Y Y Y G G P E A T L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.7 94.6 N.A. 98.3 35.7 N.A. 77.5 88.7 43.9 24.5 N.A. N.A. N.A. N.A. 42.9
Protein Similarity: 100 100 99.9 95.8 N.A. 99 53.6 N.A. 79.2 92.6 62.6 39.6 N.A. N.A. N.A. N.A. 61.2
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 100 100 0 0 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 100 100 20 0 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 64 0 0 10 0 0 0 73 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 64 10 10 0 0 % C
% Asp: 0 10 0 0 0 0 19 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 10 0 10 0 0 19 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 10 0 0 0 73 10 0 0 64 0 64 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 19 0 64 0 0 10 0 0 0 0 0 % K
% Leu: 0 64 10 0 0 0 10 0 0 0 19 0 0 0 10 % L
% Met: 0 10 0 0 0 0 0 10 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 10 10 0 0 0 0 0 0 % N
% Pro: 10 0 10 0 0 0 0 0 0 64 10 0 0 0 10 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 0 0 0 64 0 % Q
% Arg: 73 0 0 10 0 0 0 0 0 0 0 0 10 10 0 % R
% Ser: 10 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % S
% Thr: 0 10 0 10 0 0 0 0 0 10 0 0 0 10 0 % T
% Val: 0 0 73 10 0 0 0 0 0 10 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 64 10 73 10 73 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _