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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRK1
All Species:
4.55
Human Site:
T397
Identified Species:
12.5
UniProt:
Q38SD2
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q38SD2
NP_078928.3
2038
227843
T397
L
F
E
E
E
N
A
T
N
W
I
G
L
R
K
Chimpanzee
Pan troglodytes
XP_510623
2015
224902
L398
K
L
T
E
L
P
A
L
F
L
H
S
F
K
S
Rhesus Macaque
Macaca mulatta
XP_001084079
2016
225225
L398
K
L
T
E
L
P
A
L
F
L
H
S
F
K
S
Dog
Lupus familis
XP_545823
2787
308629
T1147
L
F
E
E
E
S
A
T
N
W
I
G
L
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHC2
2014
225451
Q398
R
L
T
E
L
P
V
Q
F
M
H
S
F
K
S
Rat
Rattus norvegicus
XP_218760
2013
225429
Q398
R
L
T
E
L
P
V
Q
F
M
H
S
F
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506657
1333
150378
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921165
1856
206825
N376
R
E
V
D
I
S
E
N
I
L
K
E
L
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097847
2445
271502
Q494
N
V
L
T
S
I
P
Q
E
L
F
H
L
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
96
66.4
N.A.
87.7
86.8
N.A.
48.9
N.A.
N.A.
56.1
N.A.
20.1
N.A.
N.A.
N.A.
Protein Similarity:
100
95.9
97
69.5
N.A.
92
91.7
N.A.
55.2
N.A.
N.A.
71.2
N.A.
35.4
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
13.3
93.3
N.A.
6.6
6.6
N.A.
0
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
100
N.A.
13.3
13.3
N.A.
0
N.A.
N.A.
20
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
45
0
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
12
23
67
23
0
12
0
12
0
0
12
0
0
0
% E
% Phe:
0
23
0
0
0
0
0
0
45
0
12
0
45
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
45
12
0
0
0
% H
% Ile:
0
0
0
0
12
12
0
0
12
0
23
0
0
0
0
% I
% Lys:
23
0
0
0
0
0
0
0
0
0
12
0
0
45
23
% K
% Leu:
23
45
12
0
45
0
0
23
0
45
0
0
45
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
12
0
12
23
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
45
12
0
0
0
0
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% Q
% Arg:
34
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% R
% Ser:
0
0
0
0
12
23
0
0
0
0
0
45
0
0
56
% S
% Thr:
0
0
45
12
0
0
0
23
0
0
0
0
0
0
0
% T
% Val:
0
12
12
0
0
0
23
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _