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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM161A All Species: 20.91
Human Site: S520 Identified Species: 46
UniProt: Q3B820 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3B820 NP_115556.2 660 76752 S520 P P V P T V S S R G R E Q A V
Chimpanzee Pan troglodytes XP_515502 810 93692 S614 P P V P T V S S R G R E Q A V
Rhesus Macaque Macaca mulatta XP_001114142 716 83631 S576 H Q S L A Q I S K S R V K C L
Dog Lupus familis XP_538506 813 93838 S642 P P M P T V S S R G R E Q A T
Cat Felis silvestris
Mouse Mus musculus Q8QZV6 448 52011 F329 E P F S E Y S F L K C P M L C
Rat Rattus norvegicus Q6AY14 422 48850 R304 R G K H R H R R L S P S D Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512552 616 72359 S496 P P R T N E S S R R R Q D A I
Chicken Gallus gallus XP_001232414 818 93165 S565 S P K G T Q S S Q Q R L Q A L
Frog Xenopus laevis Q66KE9 647 75309 S512 T P R S T E S S K R R E Y A I
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625188 369 43344 L251 G R Q L Q K R L R A A Q L M K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797361 773 89468 S607 P S K T T N A S E L R K S A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.3 87.4 57.6 N.A. 39 31.8 N.A. 46 37.5 41.8 N.A. N.A. N.A. 21.2 N.A. 24
Protein Similarity: 100 80.6 88.1 67 N.A. 51 44.7 N.A. 61.9 53.6 61.2 N.A. N.A. N.A. 35.7 N.A. 45.2
P-Site Identity: 100 100 13.3 86.6 N.A. 13.3 0 N.A. 46.6 46.6 46.6 N.A. N.A. N.A. 6.6 N.A. 33.3
P-Site Similarity: 100 100 33.3 93.3 N.A. 13.3 0 N.A. 60 60 60 N.A. N.A. N.A. 13.3 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 10 0 0 10 10 0 0 64 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 10 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % D
% Glu: 10 0 0 0 10 19 0 0 10 0 0 37 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 10 0 0 0 0 0 28 0 0 0 0 10 % G
% His: 10 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 19 % I
% Lys: 0 0 28 0 0 10 0 0 19 10 0 10 10 0 10 % K
% Leu: 0 0 0 19 0 0 0 10 19 10 0 10 10 10 28 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 10 10 0 % M
% Asn: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 46 64 0 28 0 0 0 0 0 0 10 10 0 0 0 % P
% Gln: 0 10 10 0 10 19 0 0 10 10 0 19 37 10 0 % Q
% Arg: 10 10 19 0 10 0 19 10 46 19 73 0 0 0 0 % R
% Ser: 10 10 10 19 0 0 64 73 0 19 0 10 10 0 0 % S
% Thr: 10 0 0 19 55 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 19 0 0 28 0 0 0 0 0 10 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _