KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROX2
All Species:
13.03
Human Site:
T168
Identified Species:
26.06
UniProt:
Q3B8N5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3B8N5
NP_001073877
592
65586
T168
Q
G
P
G
G
C
G
T
G
K
G
P
L
S
A
Chimpanzee
Pan troglodytes
XP_522907
592
65532
T168
Q
G
P
G
G
C
G
T
G
K
G
P
L
S
A
Rhesus Macaque
Macaca mulatta
XP_001088672
592
65588
T168
Q
G
P
G
G
C
G
T
R
K
G
P
L
S
A
Dog
Lupus familis
XP_858135
737
83203
S278
D
G
N
L
S
E
D
S
M
R
S
E
I
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BII1
593
65740
P167
Q
S
P
G
G
T
E
P
R
S
S
P
R
A
R
Rat
Rattus norvegicus
XP_234418
593
65234
S166
Q
S
P
G
G
T
E
S
R
S
S
L
G
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517520
680
74782
H231
R
D
P
A
K
A
R
H
G
N
H
Q
P
R
S
Chicken
Gallus gallus
Q91018
736
83123
V292
D
A
Q
A
G
D
S
V
G
R
S
D
N
E
M
Frog
Xenopus laevis
NP_001084172
740
83918
H280
N
L
S
E
D
G
M
H
S
E
I
I
D
A
R
Zebra Danio
Brachydanio rerio
NP_001121764
582
65976
S177
K
L
K
E
Q
L
Q
S
M
Q
R
L
L
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34522
586
65798
E137
A
G
K
D
G
M
E
E
H
D
D
G
M
N
D
Sea Urchin
Strong. purpuratus
XP_781578
723
81042
H229
K
L
K
G
I
L
S
H
L
Q
T
Q
L
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
93.2
33.1
N.A.
64.7
67.4
N.A.
39.7
33.4
32.2
35.1
N.A.
N.A.
N.A.
22.9
27.2
Protein Similarity:
100
97.8
95
45.4
N.A.
75.2
76.3
N.A.
49.7
45.2
46.3
48.6
N.A.
N.A.
N.A.
39.7
41.7
P-Site Identity:
100
100
93.3
6.6
N.A.
33.3
26.6
N.A.
13.3
13.3
0
6.6
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
100
93.3
26.6
N.A.
40
40
N.A.
26.6
20
13.3
26.6
N.A.
N.A.
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
17
0
9
0
0
0
0
0
0
0
25
25
% A
% Cys:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
0
9
9
9
9
0
0
9
9
9
9
9
17
% D
% Glu:
0
0
0
17
0
9
25
9
0
9
0
9
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
42
0
50
59
9
25
0
34
0
25
9
9
0
0
% G
% His:
0
0
0
0
0
0
0
25
9
0
9
0
0
9
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
9
9
9
0
0
% I
% Lys:
17
0
25
0
9
0
0
0
0
25
0
0
0
0
9
% K
% Leu:
0
25
0
9
0
17
0
0
9
0
0
17
42
9
0
% L
% Met:
0
0
0
0
0
9
9
0
17
0
0
0
9
0
9
% M
% Asn:
9
0
9
0
0
0
0
0
0
9
0
0
9
9
0
% N
% Pro:
0
0
50
0
0
0
0
9
0
0
0
34
9
0
0
% P
% Gln:
42
0
9
0
9
0
9
0
0
17
0
17
0
0
9
% Q
% Arg:
9
0
0
0
0
0
9
0
25
17
9
0
9
9
17
% R
% Ser:
0
17
9
0
9
0
17
25
9
17
34
0
0
25
9
% S
% Thr:
0
0
0
0
0
17
0
25
0
0
9
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _