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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROX2
All Species:
9.39
Human Site:
Y314
Identified Species:
18.79
UniProt:
Q3B8N5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3B8N5
NP_001073877
592
65586
Y314
K
R
L
D
S
P
R
Y
P
I
P
P
R
M
T
Chimpanzee
Pan troglodytes
XP_522907
592
65532
Y314
K
R
L
D
S
P
R
Y
L
I
P
P
R
M
I
Rhesus Macaque
Macaca mulatta
XP_001088672
592
65588
Y314
K
P
L
D
S
P
R
Y
P
I
P
P
R
M
I
Dog
Lupus familis
XP_858135
737
83203
S451
R
K
N
S
S
D
Q
S
A
S
G
P
P
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BII1
593
65740
A310
P
L
G
N
S
T
L
A
R
P
L
D
S
P
M
Rat
Rattus norvegicus
XP_234418
593
65234
A309
P
L
G
N
S
T
L
A
R
P
L
D
S
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517520
680
74782
G360
L
G
P
H
Q
P
A
G
G
L
G
P
P
L
G
Chicken
Gallus gallus
Q91018
736
83123
A456
Q
P
A
S
A
P
P
A
G
G
H
H
A
S
L
Frog
Xenopus laevis
NP_001084172
740
83918
P458
Q
S
A
S
G
P
P
P
G
S
H
H
P
S
L
Zebra Danio
Brachydanio rerio
NP_001121764
582
65976
K300
A
L
S
L
V
V
R
K
P
S
L
S
Q
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34522
586
65798
A292
E
V
L
K
Q
E
A
A
A
P
P
Q
I
P
Q
Sea Urchin
Strong. purpuratus
XP_781578
723
81042
H428
K
R
V
R
S
N
D
H
R
H
F
H
A
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
93.2
33.1
N.A.
64.7
67.4
N.A.
39.7
33.4
32.2
35.1
N.A.
N.A.
N.A.
22.9
27.2
Protein Similarity:
100
97.8
95
45.4
N.A.
75.2
76.3
N.A.
49.7
45.2
46.3
48.6
N.A.
N.A.
N.A.
39.7
41.7
P-Site Identity:
100
86.6
86.6
13.3
N.A.
6.6
6.6
N.A.
13.3
6.6
6.6
13.3
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
100
86.6
86.6
33.3
N.A.
13.3
13.3
N.A.
26.6
20
13.3
20
N.A.
N.A.
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
17
0
9
0
17
34
17
0
0
0
17
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
25
0
9
9
0
0
0
0
17
0
0
0
% D
% Glu:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
9
17
0
9
0
0
9
25
9
17
0
0
9
25
% G
% His:
0
0
0
9
0
0
0
9
0
9
17
25
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
25
0
0
9
0
25
% I
% Lys:
34
9
0
9
0
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
9
25
34
9
0
0
17
0
9
9
25
0
0
9
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
9
% M
% Asn:
0
0
9
17
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
17
17
9
0
0
50
17
9
25
25
34
42
25
25
0
% P
% Gln:
17
0
0
0
17
0
9
0
0
0
0
9
9
0
9
% Q
% Arg:
9
25
0
9
0
0
34
0
25
0
0
0
25
0
0
% R
% Ser:
0
9
9
25
59
0
0
9
0
25
0
9
17
25
0
% S
% Thr:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
9
% T
% Val:
0
9
9
0
9
9
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _