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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROX2
All Species:
1.52
Human Site:
Y354
Identified Species:
3.03
UniProt:
Q3B8N5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3B8N5
NP_001073877
592
65586
Y354
S
Q
L
L
G
H
R
Y
N
N
G
H
W
S
S
Chimpanzee
Pan troglodytes
XP_522907
592
65532
C354
S
Q
L
L
G
H
G
C
N
N
G
H
W
S
S
Rhesus Macaque
Macaca mulatta
XP_001088672
592
65588
C354
S
E
L
L
G
Y
G
C
N
N
G
H
W
S
S
Dog
Lupus familis
XP_858135
737
83203
Y491
F
P
L
P
L
M
A
Y
P
F
Q
S
P
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BII1
593
65740
M350
S
H
T
W
E
N
Q
M
L
R
Q
L
L
G
R
Rat
Rattus norvegicus
XP_234418
593
65234
I349
S
H
I
W
E
N
Q
I
L
S
Q
L
L
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517520
680
74782
G400
F
C
Q
P
L
G
S
G
Q
S
G
R
R
G
L
Chicken
Gallus gallus
Q91018
736
83123
L496
A
Y
P
F
Q
S
P
L
G
A
P
S
A
S
F
Frog
Xenopus laevis
NP_001084172
740
83918
L498
A
Y
P
F
Q
N
P
L
G
A
P
F
I
S
F
Zebra Danio
Brachydanio rerio
NP_001121764
582
65976
P340
E
H
L
L
K
F
G
P
H
S
A
F
S
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34522
586
65798
N332
G
G
G
I
F
P
P
N
F
N
A
F
N
A
F
Sea Urchin
Strong. purpuratus
XP_781578
723
81042
T468
P
N
P
S
L
H
P
T
L
A
A
S
F
M
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
93.2
33.1
N.A.
64.7
67.4
N.A.
39.7
33.4
32.2
35.1
N.A.
N.A.
N.A.
22.9
27.2
Protein Similarity:
100
97.8
95
45.4
N.A.
75.2
76.3
N.A.
49.7
45.2
46.3
48.6
N.A.
N.A.
N.A.
39.7
41.7
P-Site Identity:
100
86.6
73.3
13.3
N.A.
6.6
6.6
N.A.
6.6
6.6
6.6
13.3
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
86.6
86.6
13.3
N.A.
20
33.3
N.A.
13.3
13.3
20
33.3
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
0
9
0
0
25
25
0
9
17
0
% A
% Cys:
0
9
0
0
0
0
0
17
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
9
0
0
17
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
17
0
0
17
9
9
0
0
9
9
0
25
9
0
25
% F
% Gly:
9
9
9
0
25
9
25
9
17
0
34
0
0
25
9
% G
% His:
0
25
0
0
0
25
0
0
9
0
0
25
0
0
0
% H
% Ile:
0
0
9
9
0
0
0
9
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
42
34
25
0
0
17
25
0
0
17
17
9
17
% L
% Met:
0
0
0
0
0
9
0
9
0
0
0
0
0
9
0
% M
% Asn:
0
9
0
0
0
25
0
9
25
34
0
0
9
0
0
% N
% Pro:
9
9
25
17
0
9
34
9
9
0
17
0
9
0
0
% P
% Gln:
0
17
9
0
17
0
17
0
9
0
25
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
9
0
9
9
0
17
% R
% Ser:
42
0
0
9
0
9
9
0
0
25
0
25
9
42
25
% S
% Thr:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
17
0
0
0
0
0
0
0
0
25
0
0
% W
% Tyr:
0
17
0
0
0
9
0
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _