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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOT6
All Species:
11.82
Human Site:
S125
Identified Species:
32.5
UniProt:
Q3I5F7
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3I5F7
NP_001032239.1
207
22991
S125
E
F
Y
A
Q
I
A
S
E
R
L
Q
A
H
G
Chimpanzee
Pan troglodytes
XP_510048
483
53239
C401
E
F
Y
A
N
E
A
C
K
R
L
Q
A
H
G
Rhesus Macaque
Macaca mulatta
NP_001165423
207
23023
S125
E
F
Y
A
Q
I
A
S
E
R
L
Q
A
H
G
Dog
Lupus familis
XP_547892
445
48428
F364
D
H
N
W
K
S
E
F
Y
A
N
E
A
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q32Q92
419
46750
C337
D
V
Y
A
R
I
A
C
E
R
L
Q
A
H
G
Rat
Rattus norvegicus
O55171
453
49683
F372
D
H
N
W
K
S
E
F
Y
A
R
E
A
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520055
321
35107
S239
G
F
F
A
D
A
A
S
R
R
L
Q
S
H
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690536
480
54118
C388
A
Y
H
A
K
L
A
C
D
R
L
K
A
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169107
421
46466
S339
E
L
Y
T
Q
I
A
S
E
R
L
Q
A
H
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25
95.1
26.2
N.A.
32.9
25.8
N.A.
41.4
N.A.
N.A.
21.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
34.3
97.5
35.9
N.A.
41
35
N.A.
50.4
N.A.
N.A.
32.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
73.3
100
6.6
N.A.
73.3
6.6
N.A.
60
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
100
26.6
N.A.
86.6
26.6
N.A.
73.3
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
36.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
67
0
12
78
0
0
23
0
0
89
0
0
% A
% Cys:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% C
% Asp:
34
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
45
0
0
0
0
12
23
0
45
0
0
23
0
0
0
% E
% Phe:
0
45
12
0
0
0
0
23
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
78
% G
% His:
0
23
12
0
0
0
0
0
0
0
0
0
0
78
0
% H
% Ile:
0
0
0
0
0
45
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
34
0
0
0
12
0
0
12
0
0
23
% K
% Leu:
0
12
0
0
0
12
0
0
0
0
78
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
23
0
12
0
0
0
0
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
34
0
0
0
0
0
0
67
0
0
0
% Q
% Arg:
0
0
0
0
12
0
0
0
12
78
12
0
0
0
0
% R
% Ser:
0
0
0
0
0
23
0
45
0
0
0
0
12
23
0
% S
% Thr:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
56
0
0
0
0
0
23
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _