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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACOT6 All Species: 17.58
Human Site: S159 Identified Species: 48.33
UniProt: Q3I5F7 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3I5F7 NP_001032239.1 207 22991 S159 Y F P P S R A S V H A V L G E
Chimpanzee Pan troglodytes XP_510048 483 53239 S435 Y F P L C R A S L H A L V G S
Rhesus Macaque Macaca mulatta NP_001165423 207 23023 S159 Y F P P S R A S V H A V L G E
Dog Lupus familis XP_547892 445 48428 F398 H Y I E P P Y F P M C R A S L
Cat Felis silvestris
Mouse Mus musculus Q32Q92 419 46750 T371 Y F P P P I A T V H F V L G E
Rat Rattus norvegicus O55171 453 49683 F406 H Y I E P P Y F P L C S A G M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520055 321 35107 S273 Y F P P C L S S V P G L V K Y
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690536 480 54118 N422 Y M P F C F A N F H S V L K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001169107 421 46466 S373 Y F P M C P A S L H K I V N K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25 95.1 26.2 N.A. 32.9 25.8 N.A. 41.4 N.A. N.A. 21.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 34.3 97.5 35.9 N.A. 41 35 N.A. 50.4 N.A. N.A. 32.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 60 100 0 N.A. 73.3 6.6 N.A. 40 N.A. N.A. 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 80 100 13.3 N.A. 80 20 N.A. 60 N.A. N.A. 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. 26.6 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 36.8 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 40 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 66.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 67 0 0 0 34 0 23 0 0 % A
% Cys: 0 0 0 0 45 0 0 0 0 0 23 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 23 0 0 0 0 0 0 0 0 0 0 34 % E
% Phe: 0 67 0 12 0 12 0 23 12 0 12 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 12 0 0 56 0 % G
% His: 23 0 0 0 0 0 0 0 0 67 0 0 0 0 0 % H
% Ile: 0 0 23 0 0 12 0 0 0 0 0 12 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 12 0 0 23 12 % K
% Leu: 0 0 0 12 0 12 0 0 23 12 0 23 45 0 12 % L
% Met: 0 12 0 12 0 0 0 0 0 12 0 0 0 0 12 % M
% Asn: 0 0 0 0 0 0 0 12 0 0 0 0 0 12 0 % N
% Pro: 0 0 78 45 34 34 0 0 23 12 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % Q
% Arg: 0 0 0 0 0 34 0 0 0 0 0 12 0 0 0 % R
% Ser: 0 0 0 0 23 0 12 56 0 0 12 12 0 12 12 % S
% Thr: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 45 0 0 45 34 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 78 23 0 0 0 0 23 0 0 0 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _