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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UAP1L1 All Species: 50.91
Human Site: S473 Identified Species: 80
UniProt: Q3KQV9 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3KQV9 NP_997192.2 507 57030 S473 C E I S P L V S Y S G E G L E
Chimpanzee Pan troglodytes XP_520388 507 57028 S473 C E I S P L V S Y S G E G L E
Rhesus Macaque Macaca mulatta XP_001118204 505 56899 S471 C E I S P L I S Y A G E G L E
Dog Lupus familis XP_548360 504 55909 S473 C E I S P L V S Y A G E G L E
Cat Felis silvestris
Mouse Mus musculus Q3TW96 507 56595 S473 C E I S P L V S Y S G E G L E
Rat Rattus norvegicus NP_001127988 507 56417 S473 C E I S P L V S Y S G E G L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511500 409 45526 S377 C E I S P L V S Y F G E G L E
Chicken Gallus gallus XP_415568 501 55961 S469 C E I S P L V S Y F G E G L E
Frog Xenopus laevis NP_001086968 507 56978 S471 C E I S P L T S Y A G E G L E
Zebra Danio Brachydanio rerio Q7ZWD4 505 56395 S472 C E I S P L V S Y F G E G L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609032 520 58196 T488 C E I S P F V T Y A G E N L A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18493 484 53478 S453 I Y L K T I V S Y N G E N L Q
Sea Urchin Strong. purpuratus XP_779933 489 55054 S452 C E V S P L L S Y A G E G L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O64765 502 55741 A469 T H S V P L Y A T G V E V S P
Baker's Yeast Sacchar. cerevisiae P43123 477 53458 V441 L E D A G A I V K D G V L V E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 57.7 84.2 N.A. 82.4 83.2 N.A. 63.3 70 56.6 64.8 N.A. 48.6 N.A. 36.2 50.8
Protein Similarity: 100 99.8 72.9 90.3 N.A. 89.5 89.7 N.A. 71.4 81 72.9 78.9 N.A. 66.5 N.A. 50.8 68
P-Site Identity: 100 100 86.6 93.3 N.A. 100 100 N.A. 93.3 93.3 86.6 93.3 N.A. 66.6 N.A. 40 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 93.3 93.3 N.A. 80 N.A. 66.6 100
Percent
Protein Identity: N.A. N.A. N.A. 40 36.6 N.A.
Protein Similarity: N.A. N.A. N.A. 57 55 N.A.
P-Site Identity: N.A. N.A. N.A. 20 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 7 0 7 0 34 0 0 0 0 7 % A
% Cys: 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 7 % D
% Glu: 0 87 0 0 0 0 0 0 0 0 0 94 0 0 74 % E
% Phe: 0 0 0 0 0 7 0 0 0 20 0 0 0 0 0 % F
% Gly: 0 0 0 0 7 0 0 0 0 7 94 0 74 0 0 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 74 0 0 7 14 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 7 0 0 0 0 7 0 0 0 0 0 0 % K
% Leu: 7 0 7 0 0 80 7 0 0 0 0 0 7 87 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 7 0 0 14 0 0 % N
% Pro: 0 0 0 0 87 0 0 0 0 0 0 0 0 0 7 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 7 80 0 0 0 80 0 27 0 0 0 7 0 % S
% Thr: 7 0 0 0 7 0 7 7 7 0 0 0 0 0 0 % T
% Val: 0 0 7 7 0 0 67 7 0 0 7 7 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 7 0 87 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _