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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UAP1L1 All Species: 30.61
Human Site: S490 Identified Species: 48.1
UniProt: Q3KQV9 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3KQV9 NP_997192.2 507 57030 S490 L Q G R E F Q S P L I L D E D
Chimpanzee Pan troglodytes XP_520388 507 57028 S490 L Q G R E F Q S P L I L D E D
Rhesus Macaque Macaca mulatta XP_001118204 505 56899 A488 V A D K E F H A P L I I D E N
Dog Lupus familis XP_548360 504 55909 S490 L Q G R E F R S P F I L D E N
Cat Felis silvestris
Mouse Mus musculus Q3TW96 507 56595 S490 L Q G R Q L Q S P F I L D E D
Rat Rattus norvegicus NP_001127988 507 56417 S490 L Q G R K L Q S P F I L D E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511500 409 45526 S394 L K D K D L Q S P F I L D E H
Chicken Gallus gallus XP_415568 501 55961 S486 M K N K D F C S P F I L D E D
Frog Xenopus laevis NP_001086968 507 56978 A488 V H K H E F H A P L I I D E N
Zebra Danio Brachydanio rerio Q7ZWD4 505 56395 S489 L N Q K N L K S P F I L D E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609032 520 58196 S505 V E G K S F T S P V Y L R D S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18493 484 53478 S470 R H R E I S D S A L E S D H S
Sea Urchin Strong. purpuratus XP_779933 489 55054 P469 C N G N K F C P P I L L N Q A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O64765 502 55741 E486 S Y A G E N L E A I C R G R T
Baker's Yeast Sacchar. cerevisiae P43123 477 53458 E458 S K L S Y A G E N L S Q F K G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 57.7 84.2 N.A. 82.4 83.2 N.A. 63.3 70 56.6 64.8 N.A. 48.6 N.A. 36.2 50.8
Protein Similarity: 100 99.8 72.9 90.3 N.A. 89.5 89.7 N.A. 71.4 81 72.9 78.9 N.A. 66.5 N.A. 50.8 68
P-Site Identity: 100 100 46.6 80 N.A. 80 80 N.A. 53.3 53.3 46.6 46.6 N.A. 33.3 N.A. 20 26.6
P-Site Similarity: 100 100 80 93.3 N.A. 86.6 86.6 N.A. 73.3 80 73.3 66.6 N.A. 66.6 N.A. 20 60
Percent
Protein Identity: N.A. N.A. N.A. 40 36.6 N.A.
Protein Similarity: N.A. N.A. N.A. 57 55 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 0 7 0 14 14 0 0 0 0 0 7 % A
% Cys: 7 0 0 0 0 0 14 0 0 0 7 0 0 0 0 % C
% Asp: 0 0 14 0 14 0 7 0 0 0 0 0 74 7 34 % D
% Glu: 0 7 0 7 40 0 0 14 0 0 7 0 0 67 0 % E
% Phe: 0 0 0 0 0 54 0 0 0 40 0 0 7 0 0 % F
% Gly: 0 0 47 7 0 0 7 0 0 0 0 0 7 0 7 % G
% His: 0 14 0 7 0 0 14 0 0 0 0 0 0 7 7 % H
% Ile: 0 0 0 0 7 0 0 0 0 14 67 14 0 0 0 % I
% Lys: 0 20 7 34 14 0 7 0 0 0 0 0 0 7 0 % K
% Leu: 47 0 7 0 0 27 7 0 0 40 7 67 0 0 0 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 14 7 7 7 7 0 0 7 0 0 0 7 0 27 % N
% Pro: 0 0 0 0 0 0 0 7 80 0 0 0 0 0 0 % P
% Gln: 0 34 7 0 7 0 34 0 0 0 0 7 0 7 0 % Q
% Arg: 7 0 7 34 0 0 7 0 0 0 0 7 7 7 0 % R
% Ser: 14 0 0 7 7 7 0 67 0 0 7 7 0 0 14 % S
% Thr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % T
% Val: 20 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 0 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _