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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A35 All Species: 7.5
Human Site: Y296 Identified Species: 16.5
UniProt: Q3KQZ1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3KQZ1 NP_958928.1 300 32438 Y296 D Q L R S L Y Y T D T K _ _ _
Chimpanzee Pan troglodytes XP_001167052 237 25622
Rhesus Macaque Macaca mulatta XP_001083788 318 33722 G311 D E L R K L A G R A Q H Q G T
Dog Lupus familis XP_546609 300 32666 Y296 D Q L R T L Y Y T Y T K _ _ _
Cat Felis silvestris
Mouse Mus musculus Q5SWT3 300 32612 N296 D Q L R S F Y N T Y A K _ _ _
Rat Rattus norvegicus Q5XIF9 318 33633 L311 D E L R K L A L R A Q H P G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6GQ22 291 32540
Zebra Danio Brachydanio rerio A3KPP4 298 32266
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725361 307 34161 D298 E K L L H L R D R Y V F S Q R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789671 310 34338 Y301 D L G R K L Y Y R N F D Q N Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32332 324 35135 Y314 E Q T M K L V Y S I E S R V L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21 48.7 93.3 N.A. 91 50.9 N.A. N.A. N.A. 31 62.3 N.A. 47.8 N.A. N.A. 50.3
Protein Similarity: 100 36.6 63.2 97.3 N.A. 95 63.2 N.A. N.A. N.A. 50.6 79 N.A. 60.9 N.A. N.A. 63.8
P-Site Identity: 100 0 26.6 83.3 N.A. 66.6 26.6 N.A. N.A. N.A. 0 0 N.A. 13.3 N.A. N.A. 33.3
P-Site Similarity: 100 0 40 91.6 N.A. 66.6 40 N.A. N.A. N.A. 0 0 N.A. 26.6 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 54.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 19 0 0 19 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 55 0 0 0 0 0 0 10 0 10 0 10 0 0 0 % D
% Glu: 19 19 0 0 0 0 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 10 10 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 10 0 0 0 0 0 19 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 19 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 10 0 0 37 0 0 0 0 0 0 28 0 0 0 % K
% Leu: 0 10 55 10 0 64 0 10 0 0 0 0 0 0 10 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 10 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % P
% Gln: 0 37 0 0 0 0 0 0 0 0 19 0 19 10 10 % Q
% Arg: 0 0 0 55 0 0 10 0 37 0 0 0 10 0 10 % R
% Ser: 0 0 0 0 19 0 0 0 10 0 0 10 10 0 0 % S
% Thr: 0 0 10 0 10 0 0 0 28 0 19 0 0 0 19 % T
% Val: 0 0 0 0 0 0 10 0 0 0 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 37 37 0 28 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 28 28 28 % _