KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG6
All Species:
16.97
Human Site:
S221
Identified Species:
37.33
UniProt:
Q3KR16
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3KR16
NP_001138328.1
790
88961
S221
S
L
I
R
T
H
R
S
F
W
D
E
V
L
G
Chimpanzee
Pan troglodytes
XP_001160991
790
89043
S221
S
L
I
R
T
H
R
S
F
W
D
E
V
L
G
Rhesus Macaque
Macaca mulatta
XP_001118229
751
83748
S221
S
L
I
R
T
H
R
S
F
W
E
E
V
L
G
Dog
Lupus familis
XP_534913
800
89979
S221
S
L
I
R
V
H
K
S
F
W
E
E
V
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0J1
787
89106
R221
N
L
I
R
A
H
Q
R
F
W
E
E
V
L
Q
Rat
Rattus norvegicus
Q6RFZ7
1039
115766
G432
E
L
A
R
L
H
R
G
L
W
S
S
V
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518326
472
55138
Chicken
Gallus gallus
XP_423692
451
48811
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923813
860
97118
S199
D
I
V
Q
L
H
S
S
L
W
T
E
V
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392491
767
84898
S231
L
F
M
A
C
L
C
S
L
Q
A
S
N
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782471
866
97476
K280
V
L
E
L
A
H
T
K
F
W
K
E
N
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
83.6
80.5
N.A.
81.1
32.4
N.A.
31.1
20.6
N.A.
33.1
N.A.
N.A.
26.4
N.A.
21.4
Protein Similarity:
100
99.8
86.3
87.5
N.A.
88.2
45.2
N.A.
43.1
34
N.A.
50.5
N.A.
N.A.
44.4
N.A.
40.3
P-Site Identity:
100
100
93.3
80
N.A.
60
40
N.A.
0
0
N.A.
33.3
N.A.
N.A.
6.6
N.A.
40
P-Site Similarity:
100
100
100
93.3
N.A.
80
46.6
N.A.
0
0
N.A.
60
N.A.
N.A.
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
19
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% D
% Glu:
10
0
10
0
0
0
0
0
0
0
28
64
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
55
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
37
% G
% His:
0
0
0
0
0
73
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
46
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% K
% Leu:
10
64
0
10
19
10
0
0
28
0
0
0
0
55
28
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
19
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
10
0
0
10
0
0
0
0
10
% Q
% Arg:
0
0
0
55
0
0
37
10
0
0
0
0
0
0
0
% R
% Ser:
37
0
0
0
0
0
10
55
0
0
10
19
0
0
0
% S
% Thr:
0
0
0
0
28
0
10
0
0
0
10
0
0
0
0
% T
% Val:
10
0
10
0
10
0
0
0
0
0
0
0
64
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
73
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _