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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG6
All Species:
12.73
Human Site:
S391
Identified Species:
28
UniProt:
Q3KR16
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3KR16
NP_001138328.1
790
88961
S391
E
K
N
L
R
P
F
S
T
L
D
L
T
S
P
Chimpanzee
Pan troglodytes
XP_001160991
790
89043
S391
E
K
N
L
R
P
F
S
T
L
D
L
T
S
P
Rhesus Macaque
Macaca mulatta
XP_001118229
751
83748
F390
V
E
K
N
L
R
P
F
S
T
L
D
L
T
S
Dog
Lupus familis
XP_534913
800
89979
C391
E
K
N
L
R
P
F
C
T
L
D
L
M
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0J1
787
89106
S391
E
K
N
L
R
P
F
S
T
L
D
L
M
T
P
Rat
Rattus norvegicus
Q6RFZ7
1039
115766
L602
D
K
F
L
K
E
F
L
H
L
D
L
T
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518326
472
55138
E111
L
L
C
E
V
E
A
E
R
L
F
S
N
I
Q
Chicken
Gallus gallus
XP_423692
451
48811
S90
A
Y
E
V
V
E
G
S
T
D
E
V
D
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923813
860
97118
N369
E
R
I
L
K
E
Y
N
N
F
D
L
M
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392491
767
84898
K393
A
S
V
N
A
A
L
K
R
N
E
E
T
A
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782471
866
97476
S455
S
R
L
M
E
A
H
S
V
F
D
V
S
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
83.6
80.5
N.A.
81.1
32.4
N.A.
31.1
20.6
N.A.
33.1
N.A.
N.A.
26.4
N.A.
21.4
Protein Similarity:
100
99.8
86.3
87.5
N.A.
88.2
45.2
N.A.
43.1
34
N.A.
50.5
N.A.
N.A.
44.4
N.A.
40.3
P-Site Identity:
100
100
0
86.6
N.A.
86.6
53.3
N.A.
6.6
13.3
N.A.
33.3
N.A.
N.A.
6.6
N.A.
26.6
P-Site Similarity:
100
100
20
86.6
N.A.
93.3
73.3
N.A.
6.6
33.3
N.A.
66.6
N.A.
N.A.
20
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
10
19
10
0
0
0
0
0
0
28
0
% A
% Cys:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
10
64
10
10
0
0
% D
% Glu:
46
10
10
10
10
37
0
10
0
0
19
10
0
0
0
% E
% Phe:
0
0
10
0
0
0
46
10
0
19
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
46
10
0
19
0
0
10
0
0
0
0
0
10
0
% K
% Leu:
10
10
10
55
10
0
10
10
0
55
10
55
10
0
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
28
0
0
% M
% Asn:
0
0
37
19
0
0
0
10
10
10
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
37
10
0
0
0
0
0
0
0
64
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
19
0
0
37
10
0
0
19
0
0
0
0
0
10
% R
% Ser:
10
10
0
0
0
0
0
46
10
0
0
10
10
37
10
% S
% Thr:
0
0
0
0
0
0
0
0
46
10
0
0
37
19
0
% T
% Val:
10
0
10
10
19
0
0
0
10
0
0
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _