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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG6
All Species:
14.55
Human Site:
T495
Identified Species:
32
UniProt:
Q3KR16
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3KR16
NP_001138328.1
790
88961
T495
L
V
H
C
P
S
P
T
D
R
A
Q
W
L
E
Chimpanzee
Pan troglodytes
XP_001160991
790
89043
T495
L
V
H
C
P
S
P
T
D
R
A
Q
W
L
E
Rhesus Macaque
Macaca mulatta
XP_001118229
751
83748
S471
Q
P
L
W
Q
P
S
S
S
L
F
F
C
L
P
Dog
Lupus familis
XP_534913
800
89979
T495
I
V
H
C
P
S
A
T
D
C
A
Q
W
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0J1
787
89106
T495
T
V
H
C
P
S
S
T
E
R
A
R
W
L
E
Rat
Rattus norvegicus
Q6RFZ7
1039
115766
A706
T
F
Q
A
S
S
Q
A
L
C
R
S
W
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518326
472
55138
Y192
D
N
D
L
F
R
V
Y
V
T
W
A
E
K
H
Chicken
Gallus gallus
XP_423692
451
48811
K171
R
Q
P
L
L
V
D
K
V
V
C
R
E
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923813
860
97118
A473
C
F
Q
A
N
S
G
A
Q
G
R
S
W
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392491
767
84898
L477
L
L
L
T
D
M
L
L
I
C
K
P
S
T
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782471
866
97476
T548
D
D
Y
D
C
A
M
T
G
F
V
A
W
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
83.6
80.5
N.A.
81.1
32.4
N.A.
31.1
20.6
N.A.
33.1
N.A.
N.A.
26.4
N.A.
21.4
Protein Similarity:
100
99.8
86.3
87.5
N.A.
88.2
45.2
N.A.
43.1
34
N.A.
50.5
N.A.
N.A.
44.4
N.A.
40.3
P-Site Identity:
100
100
6.6
73.3
N.A.
73.3
13.3
N.A.
0
6.6
N.A.
20
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
100
100
13.3
86.6
N.A.
86.6
26.6
N.A.
0
20
N.A.
26.6
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
10
10
19
0
0
37
19
0
0
0
% A
% Cys:
10
0
0
37
10
0
0
0
0
28
10
0
10
0
0
% C
% Asp:
19
10
10
10
10
0
10
0
28
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
0
19
0
46
% E
% Phe:
0
19
0
0
10
0
0
0
0
10
10
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
10
10
0
0
0
0
0
% G
% His:
0
0
37
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
10
0
0
10
28
% K
% Leu:
28
10
19
19
10
0
10
10
10
10
0
0
0
55
0
% L
% Met:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
0
37
10
19
0
0
0
0
10
0
10
10
% P
% Gln:
10
10
19
0
10
0
10
0
10
0
0
28
0
0
0
% Q
% Arg:
10
0
0
0
0
10
0
0
0
28
19
19
0
0
0
% R
% Ser:
0
0
0
0
10
55
19
10
10
0
0
19
10
0
0
% S
% Thr:
19
0
0
10
0
0
0
46
0
10
0
0
0
10
0
% T
% Val:
0
37
0
0
0
10
10
0
19
10
10
0
0
10
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
10
0
64
0
0
% W
% Tyr:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _