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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG6
All Species:
8.48
Human Site:
T597
Identified Species:
18.67
UniProt:
Q3KR16
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3KR16
NP_001138328.1
790
88961
T597
Y
G
T
L
I
P
G
T
P
T
G
S
R
S
P
Chimpanzee
Pan troglodytes
XP_001160991
790
89043
T597
Y
G
T
L
I
P
G
T
P
T
G
S
R
S
P
Rhesus Macaque
Macaca mulatta
XP_001118229
751
83748
F573
D
T
D
E
D
A
P
F
V
P
D
D
T
S
D
Dog
Lupus familis
XP_534913
800
89979
D597
S
V
P
D
D
T
S
D
S
G
Y
G
T
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0J1
787
89106
S597
G
Y
S
T
L
I
P
S
S
P
K
D
S
H
S
Rat
Rattus norvegicus
Q6RFZ7
1039
115766
R808
L
S
S
P
E
F
D
R
G
P
F
S
S
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518326
472
55138
E294
E
V
D
K
L
L
K
E
F
L
R
L
D
L
T
Chicken
Gallus gallus
XP_423692
451
48811
Y273
S
A
S
I
D
S
A
Y
G
T
L
S
P
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923813
860
97118
S575
N
S
L
L
S
D
D
S
F
S
T
S
D
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392491
767
84898
N579
T
M
N
L
T
T
V
N
R
Q
H
S
S
F
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782471
866
97476
L650
S
H
G
S
S
S
S
L
Q
R
M
T
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
83.6
80.5
N.A.
81.1
32.4
N.A.
31.1
20.6
N.A.
33.1
N.A.
N.A.
26.4
N.A.
21.4
Protein Similarity:
100
99.8
86.3
87.5
N.A.
88.2
45.2
N.A.
43.1
34
N.A.
50.5
N.A.
N.A.
44.4
N.A.
40.3
P-Site Identity:
100
100
6.6
0
N.A.
0
6.6
N.A.
0
13.3
N.A.
20
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
6.6
0
N.A.
20
13.3
N.A.
6.6
33.3
N.A.
33.3
N.A.
N.A.
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
10
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
19
10
28
10
19
10
0
0
10
19
19
0
10
% D
% Glu:
10
0
0
10
10
0
0
10
0
0
0
0
10
10
10
% E
% Phe:
0
0
0
0
0
10
0
10
19
0
10
0
0
10
0
% F
% Gly:
10
19
10
0
0
0
19
0
19
10
19
10
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
10
0
0
10
0
% H
% Ile:
0
0
0
10
19
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
10
0
0
10
0
0
0
10
0
0
0
10
% K
% Leu:
10
0
10
37
19
10
0
10
0
10
10
10
0
19
10
% L
% Met:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
10
0
19
19
0
19
28
0
0
10
0
19
% P
% Gln:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
10
10
0
19
0
0
% R
% Ser:
28
19
28
10
19
19
19
19
19
10
0
55
28
37
28
% S
% Thr:
10
10
19
10
10
19
0
19
0
28
10
10
19
0
10
% T
% Val:
0
19
0
0
0
0
10
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
10
0
0
0
0
0
10
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _